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Table 7 Univariate and multivariate Cox regression analyses for recurrence-free survival in stage III colon cancers only (n = 268)

From: Associations and prognostic implications of Eastern Cooperative Oncology Group performance status and tumoral LINE-1 methylation status in stage III colon cancer patients

Parameters Univariate analysis Multivariate analysis
HR 95 % C.I. P a HR 95 % C.I. P a
T stage (T1, 2, 3 vs. T4) 2.97 1.284–6.865 0.011 2.97 1.284–6.865 0.036
N stage (N0, 1 vs. N2) 2.40 1.196–4.795 0.014 2.40 1.196–4.795 0.023
Performance status—LINE-1 methylation       
 PS(0)/LINE-1 (high) Ref.    Ref.   
 PS(0)/LINE-1 (low) 3.69 0.794–17.167 0.096 3.69 0.794–17.167 0.082
 PS(≥1)/LINE-1 (high) 1.78 0.297–10.678 0.528 1.78 0.297–10.678 0.528
 PS(≥1)/LINE-1 (low) 5.20 1.197–22.611 0.028 5.20 1.197–22.611 0.025
  1. PS performance status
  2. aCox proportional hazard regression model, adjusted for other selected covariates