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Table 2 Averaged methylation of each CpG site in control and AD groups

From: TREM2 upregulation correlates with 5-hydroxymethycytosine enrichment in Alzheimer’s disease hippocampus

CpG position 24 65 129 175 236 269 471 Total SD
MR control group. % 60.4 68.10 47.9 50.00 62.5 31.2 85.4 57.91 17.1
MR AD group. % 83.7 85.4 66.7 70.7 80.5 49.2 96.7 76.16 15.5
Gain in methylation. % 23.3 17.3 18.8 20.7 18.00 18.00 11.3 18.25 -
p value 0.0015* 0.0163 0.0353 0.0130 0.0180 0.0400 0.0121 0.0016* -
  1. CpG position denotes the position of the dinucleotide CpG within the amplicon. Total denotes the averaged methylation percentage for the whole amplicon. MR methylation ratio, AD Alzheimer’s disease, SD standard deviation. *significant after Bonferroni correction (adjusted p value = 0.00625)