Table 1 Alterations of miRNA expression level in cells transfected with native (WT) or splicing-deficient (MUT) minigenes
MicroRNA | WT minigene linea | MUT minigene linea | MUT/WT, % |
|---|---|---|---|
Hosted on conventional mirtron | |||
hsa-miR-1226-3p | 81 ± 36 | 1.5 ± 0.3 | 1.9 |
hsa-miR-1227-3p | 405 ± 204 | 24 ± 8 | 5.9 |
hsa-miR-1229-3p | 1633 ± 106 | 4.1 ± 2.1 | 0.3 |
hsa-miR-1236-3p | 747 ± 217 | 2.6 ± 0.5 | 0.3 |
hsa-miR-1238-3p | 1772 ± 1289 | 425 ± 322 | 24 |
Hosted on 5′-tailed mirtron | |||
hsa-miR-3064-5p | 27 ± 13 | 47 ± 29 | 173 |
hsa-miR-6515-5p | 875 ± 162 | 1541 ± 576 | 176 |
Hosted on 3′-tailed mirtron | |||
hsa-miR-3940-5p | 9.1 ± 1.7 | 13 ± 0.3 | 141 |
hsa-miR-6850-3p | 20 ± 12 | 57 ± 38 | 286 |