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Fig. 3 | Clinical Epigenetics

Fig. 3

From: 5-Hydroxymethylcytosine discriminates between parathyroid adenoma and carcinoma

Fig. 3

a Representative results from immunohistochemical analysis of 5hmC and TET1 in PAs (n = 4). Ad19 shows mosaic staining (M) for both (a mixture of positive and negative cells), Ad24 shows + (almost all cells stained positive regardless of strength), Ad40 shows M for 5hmC and + for TET1, and Ad55 shows VH (variable heterogeneous, areas with positive staining together with areas of negative staining). Scale bars, 50 μm (Ad 19, Ad24, Ad40) and 100 μm (Ad55). b Immunofluorescence was applied to demonstrate typical appearance of mosaic staining (M) of 5hmC at two magnifications: a scale bar 100 μm; b scale bar 50 μm

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