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Table 5 Univariate and multivariate Cox analyses on overall survival of cancer patients

From: Diagnostic and prognostic value of SHOX2 and SEPT9 DNA methylation and cytology in benign, paramalignant, and malignant ascites

  Univariate Cox analysis Multivariate Cox analysis
  Hazard ratio [95 % CI] p value Hazard ratio [95 % CI] p value
Cytology (negative as reference)     
Positive 1.20 [0.78–1.86] 0.401   
Suspicious 1.20 [0.68–2.12] 0.528   
Gender (male as reference) 0.75 [0.51–1.11] 0.153   
Age (discrete variable) 1.03 [1.01–1.05] 0.002 1.03 [1.01–1.05] 0.002
Cellular SHOX2 + SEPT9   0.014*   0.017*
Positive (negative as reference) 1.63 [1.02–2.60] 0.039 1.36 [0.84–2.19] 0.211
No DNA (negative as reference) 0.76 [0.48–1.21] 0.250 0.64 [0.40–1.03] 0.065
No DNA (positive as reference) 0.47 [0.28–0.78] 0.004 0.47 [0.28–0.79] 0.005
  1. Results of cellular DNA methylation analyses (n = 134). p values indicated by “*” refer to overall effect of the categorical variables irrespective of the reference levels