Ā | Univariate Cox analysis | Multivariate Cox analysis | ||
---|---|---|---|---|
Ā | Hazard ratio [95Ā % CI] | p value | Hazard ratio [95Ā % CI] | p value |
Tumor (negative as reference) | 2.28 [1.48ā3.53] | <0.001 | Ā | Ā |
Cytology (negative as reference) | Ā | Ā | Ā | Ā |
Positive | 2.10 [1.26ā3.51] | 0.005 | Ā | Ā |
Suspicious | 1.25 [0.54ā2.88] | 0.608 | Ā | Ā |
Gender (male as reference) | 0.76 [0.49ā1.18] | 0.217 | Ā | Ā |
Age (discrete variable) | 1.04 [1.02ā1.06] | <0.001 | 1.04 [1.02ā1.06] | <0.001 |
Cell-free SHOX2ā+āSEPT9 | Ā | 0.002* | Ā | 0.002* |
Positive (negative as reference) | 2.17 [1.26ā3.74] | 0.005 | 2.22 [1.29ā3.82] | 0.004 |
No DNA (negative as reference) | 0.85 [0.53ā1.37] | 0.498 | 0.89 [0.55ā1.44] | 0.628 |
No DNA (positive as reference) | 0.39 [0.23ā0.67] | 0.001 | 0.40 [0.23ā0.69] | 0.001 |