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Table 1 Univariate and multivariate Cox analyses on overall survival of ascites patients

From: Diagnostic and prognostic value of SHOX2 and SEPT9 DNA methylation and cytology in benign, paramalignant, and malignant ascites

Ā 

Univariate Cox analysis

Multivariate Cox analysis

Ā 

Hazard ratio [95Ā % CI]

p value

Hazard ratio [95Ā % CI]

p value

Tumor (negative as reference)

2.24 [1.64ā€“3.05]

<0.001

1.87 [1.35ā€“2.59]

<0.001

Cytology (negative as reference)

Ā Ā Ā Ā 

Positive

1.88 [1.27ā€“2.78]

0.002

Ā Ā 

Suspicious

1.54 [0.90ā€“2.63]

0.117

Ā Ā 

Gender (male as reference)

0.82 [0.60ā€“1.12]

0.207

Ā Ā 

Age (discrete variable)

1.04 [1.02ā€“1.05]

<0.001

1.03 [1.02ā€“1.05]

<0.001

Cellular SHOX2ā€‰+ā€‰SEPT9

Ā 

<0.001*

Ā 

0.003*

Positive (negative as reference)

1.97 [1.30ā€“2.97]

0.001

1.34 [0.87ā€“2.07]

0.182

No DNA (negative as reference)

0.81 [0.58ā€“1.13]

0.212

0.76 [0.54ā€“1.07]

0.121

No DNA (positive as reference)

0.41 [0.26ā€“0.64]

<0.001

0.57 [0.36ā€“0.90]

0.015

  1. Results of cellular DNA methylation analyses (nā€‰=ā€‰283). p values indicated by ā€œ*ā€ refer to overall effect of the categorical variables irrespective of the reference levels