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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Expression of epigenetic machinery genes is sensitive to maternal obesity and weight loss in relation to fetal growth in mice

Fig. 2

Body weight and metabolic parameters of OB and WL females during the preconceptional period. a Body weight. (a) P < 0.05 OB vs. CTRL, (b) P < 0.05 WL vs. CTRL, (c) P < 0.05 WL vs. OB. n = 20 CTRL, 23 OB, 19 WL. b Caloric intake. (a) P < 0.001 OB vs. CTRL, (b) P < 0.001 WL vs. CTRL, (c) P < 0.05 WL vs. OB. n = 18–20 CTRL, 23 OB, 17–19 WL. c Plasma cholesterol levels after 2 and 4 months of preconceptional diet. NS nonsignificant. (a) P < 0.001 OB vs. CTRL, (b) P < 0.001 WL vs. CTRL, (c) P < 0.001 WL vs. OB. n = 17–19 CTRL, 22–23 OB, 19 WL. d Fasting glucose level after 2 and 4 months of preconceptional diet. NS nonsignificant. (a) P < 0.05 OB vs. CTRL, (b) P < 0.05 WL vs. CTRL, (c) P < 0.05 WL vs. OB. n = 17–19 CTRL, 23 OB, 19 WL. e Plasma glucose levels during oral glucose tolerance test (OGTT) after 2 months of diet. (a) P < 0.001 OB vs. CTRL, (b) P < 0.001 WL vs. CTRL, 11–12 females per group. f Plasma glucose levels during OGTT after 4 months of diet. (a) P < 0.001 OB vs. CTRL, (c) P < 0.001 WL vs. OB, 12 females per group. Data are expressed as mean ± St. Dev (a, b, e, f) or as Tukey’s boxplot (c, d)

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Clinical Epigenetics

ISSN: 1868-7083

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