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Fig. 3 | Clinical Epigenetics

Fig. 3

From: The cardiovascular and hypothalamus-pituitary-adrenal axis response to stress is controlled by glucocorticoid receptor sequence variants and promoter methylation

Fig. 3

Haplotype 2 (BclI alone) effects of the warm (control) or ice-cold water (seCPT) condition on SBP, heart rate and cortisol over the course of the experiment. a Systolic blood pressure in millimeter of mercury after the control (left panel) or cold water (right panel). b Heart rate in beats per minute after the control (left panel) or cold water (right panel). c Salivary cortisol levels in the control (left panel) or cold water (right panel). The seCPT or warm water was administered at 23 min and lasted 3 min. In all panels, filled circles are homozygous wild-type (CC) participants and open circles are homozygous minor allele (GG) participants. Data are the mean ± the standard error of the mean

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