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Fig. 2 | Clinical Epigenetics

Fig. 2

From: H3K4 tri-methylation breadth at transcription start sites impacts the transcriptome of systemic lupus erythematosus

Fig. 2

Transcription and H3K4me3 pattern. Control samples were used to examine the relationship between gene transcription and H3K4me3 patterns. a Genes with the downstream extended H3K4me3 pattern had higher level of transcription. b Genes with the downstream extended H3K4me3 pattern had higher between sample variance of transcription. The dependence of between-sample variance on transcription level was removed using the Loess local fitting method, as genes having higher transcription tend to have higher variance too. Error bars represent standard errors, and p values were calculated by comparing each pattern to unclassified group using Wilcoxon rank-sum test

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