Skip to main content

Table 4 Overlap between DMRs and regions implicated in schizophrenia by a recent large-scale GWAS [28]

From: DNA methylation in a Scottish family multiply affected by bipolar disorder and major depressive disorder

PGC SCZ regiona DMR coordinatesa DMR gene(s) DMR comparison DMR p value DMR directionb
Chr10:18681005-18770105 Chr10:18688985-18689948 CACNB2 LH vs. MI 1.84 × 10−4 Up
Chr22: 42548710-42548874 Chr22: 42548710-42548874 LH vs. MI 1.49 × 10−5 Up
ULH vs. MI 1.85 × 10−5 Up
Chr11: 109285471-109610071 Chr11: 109294141-109294239 C11orf87 ALH vs. ULH 5.32 × 10−5 Up
Chr6: 28303247-28712247 Chr6: 28555640-28559522 Extended MHC ULH vs. MI 1.37 × 10−4 Down
  1. ahg19/GRCh37
  2. b“Up” indicates hypermethylation and “down” indicates hypomethylation compared to the reference group