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Table 6 Multivariate Cox regression overall and recurrence-free survival analysis

From: MicroRNA-100 and microRNA-21 as markers of survival and chemotherapy response in pancreatic ductal adenocarcinoma UICC stage II

Variable

Subset

Overall survival

Recurrence-free survival

  

Hazard ratio (95 % CI)

p value

Hazard ratio (95 % CI)

p value

PTEN

low/high

0.6076 (0.3351–1.1017)

0.1008

0.5431 (0.3232–0.9125)

0.0211

MDR-1

low/high

3.0434 (1.6602–5.5790)

0.0003

2.1309 (1.3164–3.4494)

0.0021

BCRP-1

low/high

0.7729 (0.3924–1.5225)

0.4565

1.3209 (0.7463–2.3378)

0.3394

microRNA-21

low/high

3.0649 (1.3709–6.8522)

0.0064

2.2521 (1.0640–4.7666)

0.0338

microRNA-100

low/high

4.8450 (1.6306–14.3961)

0.0045

1.8714 (0.7673–4.5643)

0.1683

microRNA-210

low/high

1.2116 (0.4849–3.0270)

0.6812

1.7623 (0.7634–4.0681)

0.1843

  1. Indication of hazard ratio and 95 % confidence interval (CI). p < 0.05 indicates significance