Variable | Subset | Overall survival | Recurrence-free survival | ||
---|---|---|---|---|---|
Hazard ratio (95 % CI) | p value | Hazard ratio (95 % CI) | p value | ||
PTEN | low/high | 3.095 (1.5502–6.1805) | 0.0014 | 2.7944 (1.4826–5.2669) | 0.0015 |
DCK | low/high | 0.5536 (0.2772–1.1057) | 0.0939 | 0.5178 (0.2813–0.9532) | 0.0345 |
HuR | low/high | 0.6799 (0.3448–1.3409) | 0.2656 | 0.6569 (0.3559–1.2125) | 0.1789 |
MDR-1 | low/high | 2.2213 (1.1291–4.3698) | 0.0208 | 2.5516 (1.3799–4.7179) | 0.0028 |
MRP-1 | low/high | 2.0104 (0.9778–4.1331) | 0.0576 | 2.5762 (1.3334–4.9773) | 0.0049 |
BCRP-1 | low/high | 2.7438 (1.3117–5.7395) | 0.0074 | 3.9656 (1.9563–8.0385) | 0.0001 |
VEGF-1 | low/high | 1.5977 (0.6059–4.2123) | 0.3435 | 1.3889 (0.6157–3.1331) | 0.4286 |
N | N0/N1 | 1.2670 (0.6269–2.5605) | 0.5096 | 1.16965 (0.6213–2.2018) | 0.6273 |
G | G3/G1-2 | 0.9045 (0.4425–1.8491) | 0.7833 | 0.7767 (0.4036–1.4946) | 0.4492 |
L | L0/L1 | 1.2793 (0.6478–2.5264) | 0.4781 | 1.1996 (0.6541–2.1998) | 0.5565 |
V | V0/V1 | 1.4841 (0.6944–3.1716) | 0.3083 | 1.7039 (0.8545–3.3975) | 0.1301 |
Pn | Pn0/Pn1 | 1.3512 (0.6629–2.7538) | 0.4073 | 1.2389 (0.6426–2.3889) | 0.5224 |
R | 0/1 | 1.3996 (0.6839–2.8644) | 0.3576 | 1.8921 (0.9923–3.6081) | 0.0528 |
gender | f/m | 0.9404 (0.4784–1.8487) | 0.8586 | 1.0039 (0.5444–1.8513) | 0.9899 |
age | >65/≤65 | 0.7334 (0.3747–1.4354) | 0.3655 | 0.7598 (0.4142–1.3938) | 0.3749 |
operation | DP/PD | 1.1089 (0.5034–2.4431) | 0.7974 | 1.2319 (0.5889–2.5774) | 0.5796 |
CTX response | good/bad | 23.3621 (5.5057–99.1321) | 0.00002 | 159.7685 (11.1902–2281.0912) | 0.0002 |
microRNA-21 | low/high | (2.3127) (1.1218–4.7675) | 0.0231 | 2.2006 (1.1256–4.3022) | 0.0211 |
microRNA-31* | low/high | 1.4769 (0.7365–2.9614) | 0.2719 | 1.7738 (0.9362–3.3606) | 0.0788 |
microRNA-99 | low/high | 2.2291 (1.0399–4.7781) | 0.0393 | 1.5775 (0.8023–3.1019) | 0.1864 |
microRNA-100 | low/high | 4.0097 (1.7189–9.3536) | 0.0013 | 2.3653 (1.1714–4.7762) | 0.0163 |
microRNA-125b | low/high | 2.1879 (0.9745–4.9127) | 0.0578 | 2.0935 (1.0093–43426) | 0.0472 |
microRNA-138 | low/high | 1.4770 (0.6583–3.3141) | 0.3442 | 1.3268 (0.6556–2.6854) | 0.4318 |
microRNA-147b | low/high | 0.8217 (0.4094–1.6489) | 0.5805 | 0.7387 (0.3891–1.4022) | 0.3543 |
microRNA-148a | low/high | 0.9135 (0.4533–1.8411) | 0.8003 | 1.1714 (0.6249–2.1957) | 0.6217 |
microRNA-210 | low/high | 2.4021 (1.1408–5.0578) | 0.0211 | 2.2881 (1.1611–4.5091) | 0.0168 |
microRNA-376a | low/high | 1.9456 (0.9518–3.9771) | 0.0681 | 1.7029 (0.8906–3.2563) | 0.1075 |