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Table 3 MicroRNA expression of PDAC patients with good and poor chemotherapy (w CTX) response

From: MicroRNA-100 and microRNA-21 as markers of survival and chemotherapy response in pancreatic ductal adenocarcinoma UICC stage II

 

Control vs. PDAC w CTX good response

Control vs. PDAC w CTX bad response

PDAC w CTX good response vs. PDAC w CTX bad response

microRNA-21

2.89 vs. 1.39 (+51.6 %)

p = 4.3817E-07

2.89 vs. 0.86 (+70.3 %)

p = 3.3364E-09

1.39 vs. 0.86 (+38.7 %)

p = 0.0295

microRNA-31*

15.02 vs. 12.74 (+15.2 %)

p = 0.0003

15.02 vs. 12.10 (+19.4 %)

p = 1.3354E-05

12.74 vs. 12.10 (+5.0 %)

p = 0.2232

microRNA-99a

6.23 vs. 5.61 (+10.0 %)

p = 0.0406

6.23 vs. 5.09 (+18.4 %)

p = 0.0004

5.61 vs. 5.09 (+9.3 %)

p = 0.0370

microRNA-100

6.91 vs. 5.18 (+25.0 %)

p = 4.0492E-08

6.91 vs. 4.69 (+32.2 %)

p = 2.9936E-11

5.18 vs. 4.69 (+9.5 %)

p = 0.0275

microRNA-125b

3.34 vs. 2.57 (+22.9 %)

p = 0.0001

3.34 vs. 2.31 (+30.8 %)

p = 0.0001

2.57 vs. 2.31 (+10.2 %)

p = 0.1968

microRNA-138

13.08 vs. 12.19 (+6.8 %)

p = 0.0301

13.08 vs. 11.95 (+8.7 %)

p = 0.0082

12.19 vs. 11.95 (+2.0 %)

p = 0.4705

microRNA-147b

14.57 vs. 13.44 (+7.8 %)

p = 0.0028

14.57 vs. 13.49 (+7.4 %)

p = 0.0105

13.44 vs. 13.49 (−0.4 %)

p = 0.8662

microRNA-148a

0.69 vs. 5.03 (−622.1 %)

p = 3.9814E-09

0.69 vs. 5.29 (−660.5 %)

p = 2.1259E-12

5.03 vs. 5.29 (−5.3 %)

p = 0.5821

microRNA-210

9.17 vs. 8.26 (+9.9 %)

p = 0.0044

9.17 vs. 7.56 (+17.6 %)

p = 4.9353E-05

8.26 vs. 7.56 (+8.5 %)

p = 0.0208

microRNA-376a

16.39 vs. 15.82 (+3.5 %)

p = 0.1332

16.39 vs. 15.28 (+6.8 %)

p = 0.0026

15.82 vs. 15.28 (+3.4 %)

p = 0.0849

  1. Benign, noninflammatory pancreatic specimens of patients with pancreatic cystadenoma or papillary adenoma served as controls. All data are given as median ΔCt level expression differences in percent. p < 0.05 indicates significance