Table 1 EPICOR and EPIC-NL sample descriptive
EPICOR men | EPICOR women | EPIC-NL men | EPIC-NL women | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cases | Controls | Cases | Controls | Cases | Controls | Cases | Controls | |||||||
(N = 188) | (N = 188) | (N = 104) | (N = 104) | (N = 116) | (N = 83) | (N = 201) | (N = 179) | |||||||
n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | |||||||
Center | ||||||||||||||
Varese | 42 (22.34) | 42 (22.34) | 67 (65.69) | 67 (65.69) | ||||||||||
Ragusa | 19 (10.11) | 19 (10.11) | 3 (2.94) | 3 (2.94) | ||||||||||
Turin | 127 (67.55) | 127 (67.55) | 23 (22.55) | 23 (22.55) | ||||||||||
Naples | – | – | 11 (10.78) | 11 (10.78) | ||||||||||
Utrecht | – | – | 149 (74.13) | 140 (78.21) | ||||||||||
Bilthoven | 116 (100) | 83 (100) | 52 (25.87) | 39 (21.79) | ||||||||||
Smoking status | ||||||||||||||
Never | 33 (17.55) | 50 (26.60) |
| 53 (50.96) | 73 (70.19) |
| 19 (16.38) | 18 (21.69) | 60 (29.85) | 85 (47.49) |
| |||
Former | 70 (37.23) | 87 (46.28) | * | 11 (10.58) | 13 (12.50) | * | 34 (29.31) | 32 (38.55) | 48 (23.88) | 48 (26.81) | * | |||
Current | 85 (45.21) | 51 (27.13) | 40 (38.46) | 18 (17.31) | 62 (53.45) | 33 (39.76) | 89 (44.28) | 45 (25.14) | ||||||
NA | 1 (0.86) | 4 (1.99) | 1 (0.56) | |||||||||||
Menopausal Status | ||||||||||||||
Premenopause | 27 (25.96) | 26 (25.00) | 43 (21.39) | 42 (23.46) | ||||||||||
Post-menopause | 77 (74.04) | 78 (75.00) | 158 (78.61) | 137 (76.54) | ||||||||||
Mean ± sd | Mean ± sd | Mean ± sd | Mean ± sd | Mean ± sd | Mean ± sd | Mean ± sd | Mean ± sd | |||||||
Age at recruitment (years) | 50.98 ± 6.93 | 50.92 ± 7.01 | 55.02 ± 7.40 | 55.01 ± 7.51 | 51.51 ± 7.68 | 51.11 ± 8.30 | 58.56 ± 8.74 | 59.30 ± 8.12 | ||||||
Avg. follow-up (years) | 12.98 ± 2.29 | 13.26 ± 2.06 | 12.24 ± 1.97 | 12.66 ± 1.16 | 13.07 ± 5.21 | 15.25 ± 2.31** | 11.61 ± 4.92 | 14.27 ± 2.62** | ||||||
Avg. TTD (years) | 7.14 ± 3.88 | – | 6.54 ± 3.57 | – | 5.44 ± 3.22 | – | 5.76 ± 3.06 | – | ||||||
BMI (kg/m2) | 27.05 ± 2.96 | 26.35 ± 3.12** | 26.95 ± 4.69 | 25.93 ± 5.11 | 27.12 ± 3.30 | 27.08 ± 3.15 | 26.47 ± 4.24 | 26.05 ± 4.17 | ||||||
WHR | 0.94 ± 0.06 | 0.93 ± 0.06** | 0.83 ± 0.06 | 0.79 ± 0.06** | 0.95 ± 0.08 | 0.94 ± 0.08 | 0.82 ± 0.07 | 0.80 ± 0.07** | ||||||
Total cholesterol (mmol/L) | 6.10 ± 1.12 | 5.86 ± 1.22 | 6.42 ± 1.23 | 6.36 ± 1.16 | 6.24 ± 0.95 | 5.79 ± 0.97** | 5.51 ± 0.98 | 5.27 ± 0.98** | ||||||
LDL cholesterol (mmol/L) | 3.94 ± 1.00 | 3.60 ± 1.01** | 4.07 ± 1.15 | 3.97 ± 1.01 | 3.60 ± 0.94 | 3.34 ± 0.92 | 3.44 ± 0.82 | 3.19 ± 0.77** | ||||||
HDL cholesterol (mmol/L) | 1.30 ± 0.29 | 1.48 ± 0.37** | 1.55 ± 0.39 | 1.76 ± 0.41** | 1.11 ± 0.28 | 1.12 ± 0.28 | 1.16 ± 0.33 | 1.27 ± 0.36** | ||||||
Triglycerides (mmol/L) | 1.89 ± 0.99 | 1.71 ± 1.04 | 1.74 ± 1.43 | 1.38 ± 0.57** | 2.28 ± 1.27 | 2.28 ± 1.46 | 1.77 ± 0.98 | 1.54 ± 0.91** | ||||||
SBP (mmHg) | 137.47 ± 16.56 | 135.04 ± 19.03 | 144.36 ± 9.77 | 136.76 ± 10.08** | 134.43 ± 17.61 | 128.51 ± 14.93** | 138.50 ± 22.23 | 133.59 ± 20.76** | ||||||
DBP (mmHg) | 85.38 ± 8.96 | 84.97 ± 10.80 | 86.08 ± 22.13 | 84.97 ± 19.02 | 84.96 ± 10.71 | 80.60 ± 10.19** | 81.99 ± 11.20 | 79.22 ± 11.18** | ||||||
Alcohol (gr/day) | 23.46 ± 20.26 | 24.98 ± 20.90 | 6.29 ± 10.78 | 8.76 ± 15.43 | 19.42 ± 21.89 | 18.41 ± 22.27 | 7.55 ± 11.24 | 8.44 ± 12.21 | ||||||
