Fig. 1

Graphs showing the difference in DNA methylation (∆β) at age 10 between each pair of monozygotic (MZ) twins discordant for asthma (affected twin − unaffected co-twin) for each of the ten top-ranked differentially methylated positions (DMPs). Mean within-twin pair ∆β across all 37 MZ twin pairs is highlighted in red. Error bars represent the ±standard deviation. Consistent within-twin pair differences in DNA methylation at age 10 are observed across asthma-discordant MZ twin pairs at the top ten ranked differentially methylated positions