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Table 2 GSEA on FEM modules revealed strong enrichment of two FEMs with seed genes CAV1 and FSTL1, respectively

From: The integrative epigenomic-transcriptomic landscape of ER positive breast cancer

FEM Size Enriched pathway Overlap Overlapping genes
CAV1 58 WNT signalling 23 DKK1 WNT3A FZD9 WNT2 WNT7A IGFBP4
FZD8 FZD1 LRP6 FZD2 LRP5 FZD6 RSPO1
WNT5A RYK FZD5 ATP6AP2 WNT3 WIF1
WNT1 WNT7B FZD10 SFRP1
FSTL1 56 TGF-beta signalling 18 NOG GDF5 CHRD TGFB2 TGFB1 FST TGFB3
BMPR2 GDF6 BMPR1A BMPR1B ACVRL1
ACVR2A BMP4 BMP2 BMP7 BMP6 INHBE
  1. Columns label the FEM module size, the main enriched pathway, the number of overlapping genes between FEM and pathway and the overlapping genes
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