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Fig. 3 | Clinical Epigenetics

Fig. 3

From: The integrative epigenomic-transcriptomic landscape of ER positive breast cancer

Fig. 3

Integrative clustering of matched DNAm and mRNA data in ER+ breast cancer. Result of the integrative iCluster algorithm on 545 ER+ breast cancer samples with matched DNAm and mRNA expression. The algorithm predicted two main clusters, which are depicted together with the normal samples, as indicated in the top barcode. The second barcode shows the distribution of PAM50 intrinsic subtypes across the clusters. Genes have been ordered according to the FEM module they belong too, as indicated. Left heatmap is for DNAm, right heatmap for mRNA expression

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