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Table 1 Baseline characteristics of the subjects enrolled in the study

From: Promoter methylation status and expression of PPAR-γ gene are associated with prognosis of acute-on-chronic hepatitis B liver failure

 

ACHBLF

CHB

HC

Cases (n)

81

50

30

Age (years)

44.25 ± 13.65

41.80 ± 14.04

41.57 ± 12.09

Gender (m/f)

57/24

35/15

21/9

HBeAg (+/-)

37/44

23/27

0/30

Log10 [HBV DNA]

5.16 ± 1.71

5.64 ± 1.64

NA

ALT (U/L)

489.45 ± 642.68*,**

362.92 ± 470.21*

27.10 ± 11.55

AST (U/L)

398.61 ± 534.34*,**

183.40 ± 202.84*

26.77 ± 7.34

TBIL (μmol/L)

296.43 ± 158.18*,**

30.19 ± 38.44*

12.48 ± 5.08

Cr (μmol/L)

73.35 ± 42.66*,**

63.34 ± 13.64*

57.33 ± 12.79

ALB (g/L)

33.48 ± 8.73*,**

40.86 ± 5.67*

47.00 ± 4.53

PTA (%)

37.84 ± 9.06*,**

91.94 ± 17.39

93.60 ± 14.17

INR

1.87 ± 0.63*,**

1.02 ± 0.14

1.01 ± 0.11

Ascites (%)

76.54*,**

24.00*

0

Encephalopathy (%)

34.57*,**

0

0

Mortality (%)

54.32*,**

0

0

  1. Data are shown as mean ± standard deviation
  2. ACHBLF acute-on-chronic hepatitis B liver failure, CHB chronic hepatitis B, HC healthy control, HBV Hepatitis B virus, ALT alanine aminotransferase, AST aspartate aminotransferase, TBIL total bilirubin, Cr serum creatinine, ALB albumin, PTA prothrombin activity, INR international normalized ratio, NA not available
  3. *Versus HC P < 0.05; **Versus CHB P < 0.05