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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Circulating nucleosomes as epigenetic biomarkers in pancreatic cancer

Fig. 2

ROC curve for discrimination of cancer vs. healthy and benign. The area under the curve for an optimal panel of five nucleosomal biomarkers (0.92) selected from a panel of nine was significantly higher than that of CA 19-9 (0.85), the current gold standard for pancreatic cancer. The AUC was further improved by replacing the lowest weighted nucleosomal biomarker in model 1 with CA 19-9 in a panel with the four nucleosomal biomarkers (0.94) to give a second, mixed biomarker, model

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