Fig. 1
From: Circulating nucleosomes as epigenetic biomarkers in pancreatic cancer
Discrimination of five NuQ® assay panel for pancreatic cancer, benign disease, and healthy controls. Significant separation (p < 0.001) between the pancreatic cancer (n = 25), the benign samples (n = 10), and healthy controls (n = 24) was achieved with pre-processed ELISA data from five nucleosomal biomarkers. A linear model (Fisher’s linear discriminant) was used to generate a weighted sum of values assigned as arbitrary units (AU) = −0.825 (5MC) − 2.909 (H2AZ) + 2.641 (H2A1.1) − 1.050 (H3K4Me2) − 0.551 (H2AK119Ub). P value was determined by the Mann-Whitney U test. Box plots indicate the median and 25th and 75th percentiles. Whiskers indicate the 5th and 95th percentiles