Skip to main content
Fig. 4 | Clinical Epigenetics

Fig. 4

From: Analysis of DNA methylation landscape reveals the roles of DNA methylation in the regulation of drug metabolizing enzymes

Fig. 4

Representative results of correlation analysis. A significant inverse correlation between DNA methylation level (β value) and mRNA expression level was detected for the CYP2C19 (a) and GSTA4 (c) genes (p < 0.05, Spearman’s rank correlation test). The level of mRNA expression, shown as the vertical axis, was normalized to the expression level of ACTB (set as 100 %). CpG sites with significant correlations are indicated by asterisks in methylation mapping for the CYP2C19 (b) and GSTA4 (d) genes. Additionally, CpG sites with β R values of more than 0.296 are indicated by circles

Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us