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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Whole-genome bisulfite sequencing of cell-free DNA identifies signature associated with metastatic breast cancer

Fig. 4

Comparison of WGBS to MiSeq (targeted amplicon sequencing). a Box plots representing percent methylation for DMLs in GP5, HTR1B, PCDH10, and UNC13A as called by both technologies. b Mean-Whisker plots displaying average methylation state of all amplicons assayed by MiSeq and WGBS. c Scatter plot of percent methylation value for the 36 CpGs assayed in H, DFS, and MBC by both MiSeq and WGBS. The correlation is reported as R 2 = 0.768. d Pearson correlation coefficient for WGBS versus MiSeq for 36 CpGs assayed by targeted amplicon sequencing

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