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Table 3 Pathways enriched for differentially expressed genes with DMS

From: The epigenetic signature of subcutaneous fat cells is linked to altered expression of genes implicated in lipid metabolism in obese women

 

Number of genes

 

Wikipathway

Observed

Expected

Total

Adjusted P

Focal adhesion

47

9.25

185

1.52 × 10−18

Adipogenesis

31

6.5

130

1.66 × 10−11

Regulation of toll-like receptor signaling

33

7.7

154

4.77 × 10−11

Integrated Pancreatic Cancer Pathway

35

9.05

181

1.73 × 10−10

MAPK signaling pathway

33

8.25

165

2.12 × 10−10

B Cell Receptor Signaling Pathway

26

5.7

114

1.21 × 10−9

TCR Signaling Pathway

25

5.3

106

1.21 × 10−9

Insulin Signaling

31

8.15

163

1.91 × 10−09

Muscle cell TarBase

55

21.21

424

1.91 × 10−09

Regulation of Actin Cytoskeleton

30

7.85

157

3.00 × 10−09

DNA damage response

22

4.38

89

2.97 × 10−09

Integrin-mediated cell adhesion

23

4.97

101

6.25 × 10−09

AGE-RAGE pathway

19

3.74

76

3.36 × 10−08

IL-3 Signaling Pathway

16

2.66

54

3.68 × 10−08

Fatty Acid Biosynthesis

12

1.43

29

3.99 × 10−08