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Table 3 Pathways enriched for differentially expressed genes with DMS

From: The epigenetic signature of subcutaneous fat cells is linked to altered expression of genes implicated in lipid metabolism in obese women

  Number of genes  
Wikipathway Observed Expected Total Adjusted P
Focal adhesion 47 9.25 185 1.52 × 10−18
Adipogenesis 31 6.5 130 1.66 × 10−11
Regulation of toll-like receptor signaling 33 7.7 154 4.77 × 10−11
Integrated Pancreatic Cancer Pathway 35 9.05 181 1.73 × 10−10
MAPK signaling pathway 33 8.25 165 2.12 × 10−10
B Cell Receptor Signaling Pathway 26 5.7 114 1.21 × 10−9
TCR Signaling Pathway 25 5.3 106 1.21 × 10−9
Insulin Signaling 31 8.15 163 1.91 × 10−09
Muscle cell TarBase 55 21.21 424 1.91 × 10−09
Regulation of Actin Cytoskeleton 30 7.85 157 3.00 × 10−09
DNA damage response 22 4.38 89 2.97 × 10−09
Integrin-mediated cell adhesion 23 4.97 101 6.25 × 10−09
AGE-RAGE pathway 19 3.74 76 3.36 × 10−08
IL-3 Signaling Pathway 16 2.66 54 3.68 × 10−08
Fatty Acid Biosynthesis 12 1.43 29 3.99 × 10−08