Fig. 2From: Exploration of hydroxymethylation in Kagami-Ogata syndrome caused by hypermethylation of imprinting control regionsRepresentative data of BS/oxBS-array. a Density plots of normalized beta values with BS and oxBS conversion for three KOS14 blood samples (Pt1–Pt3), one control pooled blood sample, and one control adult brain sample. Beta values show a bimodal distribution for both BS and oxBS conversion samples. Of note, a left-skewed methylated peak is observed in the oxBS brain sample. b Box and whisker plots of Δβ score (corresponding to 5hmC value) for each sample. c Distribution of probes with Δβ ≥ 0.1 according to genomic features for each sampleBack to article page