Table 1 Spatial relationships between genomic intervals of top DMRs and selected genomic features

Statistical concept

Interpretation

SINE

LINE

LTR

DNAt

snRNA

Low

CpGi

Genes

SINE

LINE

LTR

DNAt

snRNA

Low

CpGi

Genes

Reference population

Number entities within each class

1769839

1480369

708210

456948

4285

367822

27718

23033

1769839

1480369

708210

456948

4285

367822

27718

23033

Relative KS p-value

Relative relationship between interval midpoints

<0.05

n.s.

n.s.

n.s.

n.s.

<0.1

n.s.

<0.1

<0.0001

<0.01

n.s.

n.s.

n.s.

<0.05

n.s.

n.s.

Type of relationship

Positive

–

–

–

–

Negative

–

Positive

Positive

Negative

–

–

–

Negative

–

–

Jaccard Measure p-value

Ovelaps between intervals

< 0.0001

<0.01

<0.1

n.s.

n.s.

<0.05

n.s.

<0.0001

<0.0001

<0.001

n.s.

n.s.

n.s.

n.s.

n.s.

<0.1

Type of overlap

Positive

Negative

Positive

–

–

Negative

–

Positive

Positive

Negative

–

–

–

–

–

Positive