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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Global analysis of DNA methylation in hepatocellular carcinoma by a liquid hybridization capture-based bisulfite sequencing approach

Fig. 4

Demonstration of epigenetic regulation of candidate gene transcription. a Methylation and transcript expression levels of candidate genes in HCT116 and DKO cell lines are shown. b Demethylation assay using DAC treatment; mRNA levels of CCL20 and IFITM1 were confirmed. For RT-PCR results in b, the quantitative ratios were normalized to the expression of GAPDH. Data are representative of three similar experiments and displayed as mean ± SD. *P value <0.05; **P value <0.01, as evaluated by Student’s t test

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Clinical Epigenetics

ISSN: 1868-7083

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