Fig. 7

Methylation at PAR regions. a MeDIP-based data. Lower panel shows the scatter plot with smooth curve fitted by Loess (without gaps). Three different parts separately represent the PAR1, PAR2 and the non-PAR region. The upper panel highlights the raw MeDIP data as shown by the SignalMap software for the loci that were also studied by pyrosequencing (shown in part B of the Figure). b Pyrosequencing at two loci in PAR2: SYBL1 and CpG29. The p values of Kruskal-Wallis test for multiple group comparison are shown below the name of the locus; the Mann-Whitney p values of individual comparisons when significant are shown in grey. In the middle of the figure, a diagram of the X chromosome is displayed together with the transcripts and their level of expression (on a scale of 0 to 9 to the left of the figure). T.S Turner syndrome