TY - JOUR AU - Mantovani, A. AU - Allavena, P. AU - Sica, A. AU - Balkwill, F. PY - 2008 DA - 2008// TI - Cancer-related inflammation JO - Nature VL - 454 UR - https://doi.org/10.1038/nature07205 DO - 10.1038/nature07205 ID - Mantovani2008 ER - TY - JOUR AU - Colotta, F. AU - Allavena, P. AU - Sica, A. AU - Garlanda, C. AU - Mantovani, A. PY - 2009 DA - 2009// TI - Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability JO - Carcinogenesis VL - 30 UR - https://doi.org/10.1093/carcin/bgp127 DO - 10.1093/carcin/bgp127 ID - Colotta2009 ER - TY - JOUR AU - Grivennikov, S. I. AU - Greten, F. R. AU - Karin, M. PY - 2010 DA - 2010// TI - Immunity, inflammation, and cancer JO - Cell VL - 140 UR - https://doi.org/10.1016/j.cell.2010.01.025 DO - 10.1016/j.cell.2010.01.025 ID - Grivennikov2010 ER - TY - JOUR AU - Aggarwal, B. B. AU - Vijayalekshmi, R. V. AU - Sung, B. PY - 2009 DA - 2009// TI - Targeting inflammatory pathways for prevention and therapy of cancer: short-term friend, long-term foe JO - Clin Cancer Res VL - 15 UR - https://doi.org/10.1158/1078-0432.CCR-08-0149 DO - 10.1158/1078-0432.CCR-08-0149 ID - Aggarwal2009 ER - TY - JOUR AU - Cathcart, M. C. AU - Lysaght, J. AU - Pidgeon, G. P. PY - 2011 DA - 2011// TI - Eicosanoid signalling pathways in the development and progression of colorectal cancer: novel approaches for prevention/intervention JO - Cancer Metastasis Rev VL - 30 UR - https://doi.org/10.1007/s10555-011-9324-x DO - 10.1007/s10555-011-9324-x ID - Cathcart2011 ER - TY - JOUR AU - Greenhough, A. AU - Smartt, H. J. M. AU - Moore, A. E. AU - Roberts, H. R. AU - Williams, A. C. AU - Paraskeva, C. PY - 2009 DA - 2009// TI - The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment JO - Carcinogenesis VL - 30 UR - https://doi.org/10.1093/carcin/bgp014 DO - 10.1093/carcin/bgp014 ID - Greenhough2009 ER - TY - JOUR AU - Wang, D. AU - Dubois, R. N. PY - 2010 DA - 2010// TI - The role of COX-2 in intestinal inflammation and colorectal cancer JO - Oncogene VL - 29 UR - https://doi.org/10.1038/onc.2009.421 DO - 10.1038/onc.2009.421 ID - Wang2010 ER - TY - JOUR AU - Coghill, A. E. AU - Newcomb, P. A. AU - Poole, E. M. AU - Hutter, C. M. AU - Makar, K. W. AU - Duggan, D. PY - 2011 DA - 2011// TI - Genetic variation in inflammatory pathways is related to colorectal cancer survival JO - Clin Cancer Res VL - 17 UR - https://doi.org/10.1158/1078-0432.CCR-11-1134 DO - 10.1158/1078-0432.CCR-11-1134 ID - Coghill2011 ER - TY - JOUR AU - Resler, A. J. AU - Makar, K. W. AU - Heath, L. AU - Whitton, J. AU - Potter, J. D. AU - Poole, E. M. PY - 2014 DA - 2014// TI - Genetic variation in prostaglandin synthesis and related pathways, NSAID use and colorectal cancer risk in the Colon Cancer Family Registry JO - Carcinogenesis VL - 35 UR - https://doi.org/10.1093/carcin/bgu119 DO - 10.1093/carcin/bgu119 ID - Resler2014 ER - TY - JOUR AU - Poole, E. M. AU - Hsu, L. AU - Xiao, L. AU - Kulmacz, R. J. AU - Carlson, C. S. AU - Rabinovitch, P. S. PY - 2010 DA - 2010// TI - Genetic variation in prostaglandin E2 synthesis and signaling, prostaglandin dehydrogenase, and the risk of colorectal adenoma JO - Cancer Epidemiol Biomarkers Prev VL - 19 UR - https://doi.org/10.1158/1055-9965.EPI-09-0869 DO - 10.1158/1055-9965.EPI-09-0869 ID - Poole2010 ER - TY - JOUR AU - Cox, D. G. AU - Pontes, C. AU - Guino, E. AU - Navarro, M. AU - Osorio, A. AU - Canzian, F. PY - 2004 DA - 2004// TI - Polymorphisms in prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/COX2) and risk of colorectal cancer JO - Br J Cancer VL - 91 ID - Cox2004 ER - TY - JOUR AU - Rigas, B. AU - Goldman, I. S. AU - Levine, L. PY - 1993 DA - 1993// TI - Altered eicosanoid levels in human colon cancer JO - J Lab Clin Med VL - 122 ID - Rigas1993 ER - TY - JOUR AU - Pugh, S. AU - Thomas, G. A. PY - 1994 DA - 1994// TI - Patients with adenomatous polyps and carcinomas have increased colonic mucosal prostaglandin E2 JO - Gut VL - 35 UR - https://doi.org/10.1136/gut.35.5.675 DO - 10.1136/gut.35.5.675 ID - Pugh1994 ER - TY - JOUR AU - Ogino, S. AU - Kirkner, G. J. AU - Nosho, K. AU - Irahara, N. AU - Kure, S. AU - Shima, K. PY - 2008 DA - 2008// TI - Cyclooxygenase-2 expression is an independent predictor of poor prognosis in colon cancer JO - Clin Cancer Res VL - 14 UR - https://doi.org/10.1158/1078-0432.CCR-08-1841 DO - 10.1158/1078-0432.CCR-08-1841 ID - Ogino2008 ER - TY - JOUR AU - Tsujii, M. AU - Kawano, S. AU - DuBois, R. N. PY - 1997 DA - 1997// TI - Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential JO - Proc Natl Acad Sci U S A VL - 94 UR - https://doi.org/10.1073/pnas.94.7.3336 DO - 10.1073/pnas.94.7.3336 ID - Tsujii1997 ER - TY - JOUR AU - Kunzmann, A. T. AU - Murray, L. J. AU - Cardwell, C. R. AU - McShane, C. M. AU - McMenamin, U. C. AU - Cantwell, M. M. PY - 2013 DA - 2013// TI - PTGS2 (Cyclooxygenase-2) expression and survival among colorectal cancer patients: a systematic review JO - Cancer Epidemiol Biomarkers Prev VL - 22 UR - https://doi.org/10.1158/1055-9965.EPI-13-0263 DO - 10.1158/1055-9965.EPI-13-0263 ID - Kunzmann2013 ER - TY - STD TI - Kurtova AV, Xiao J, Mo Q, Pazhanisamy S, Krasnow R, Lerner SP et al. Blocking PGE-induced tumour repopulation abrogates bladder cancer chemoresistance. Nature. 2014;517:209–13. ID - ref17 ER - TY - JOUR AU - Tougeron, D. AU - Sha, D. AU - Manthravadi, S. AU - Sinicrope, F. A. PY - 2014 DA - 2014// TI - Aspirin and colorectal cancer: back to the future JO - Clin Cancer Res VL - 20 UR - https://doi.org/10.1158/1078-0432.CCR-13-2563 DO - 10.1158/1078-0432.CCR-13-2563 ID - Tougeron2014 ER - TY - JOUR AU - Sahin, I. H. AU - Hassan, M. M. AU - Garrett, C. R. PY - 2014 DA - 2014// TI - Impact of non-steroidal anti-inflammatory drugs on gastrointestinal cancers: current state-of-the science JO - Cancer Lett VL - 345 UR - https://doi.org/10.1016/j.canlet.2013.09.001 DO - 10.1016/j.canlet.2013.09.001 ID - Sahin2014 ER - TY - JOUR AU - Thun, M. J. AU - Jacobs, E. J. AU - Patrono, C. PY - 2012 DA - 2012// TI - The role of aspirin in cancer prevention JO - Nat Rev Clin Oncol VL - 9 UR - https://doi.org/10.1038/nrclinonc.2011.199 DO - 10.1038/nrclinonc.2011.199 ID - Thun2012 ER - TY - JOUR AU - Liao, X. AU - Lochhead, P. AU - Nishihara, R. AU - Morikawa, T. AU - Kuchiba, A. AU - Yamauchi, M. PY - 2012 DA - 2012// TI - Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival JO - N Engl J Med VL - 367 UR - https://doi.org/10.1056/NEJMoa1207756 DO - 10.1056/NEJMoa1207756 ID - Liao2012 ER - TY - JOUR AU - Ulrich, C. M. AU - Bigler, J. AU - Potter, J. D. PY - 2006 DA - 2006// TI - Non-steroidal anti-inflammatory drugs for cancer prevention: promise, perils and pharmacogenetics JO - Nat Rev Cancer VL - 6 UR - https://doi.org/10.1038/nrc1801 DO - 10.1038/nrc1801 ID - Ulrich2006 ER - TY - JOUR AU - Ng, K. AU - Meyerhardt, J. A. AU - Chan, A. T. AU - Sato, K. AU - Chan, J. A. AU - Niedzwiecki, D. PY - 2015 DA - 2015// TI - Aspirin and COX-2 inhibitor use in patients with stage III colon cancer JO - J Natl Cancer Inst VL - 107 UR - https://doi.org/10.1093/jnci/dju345 DO - 10.1093/jnci/dju345 ID - Ng2015 ER - TY - JOUR AU - Din, F. V. AU - Theodoratou, E. AU - Farrington, S. M. AU - Tenesa, A. AU - Barnetson, R. A. AU - Cetnarskyj, R. PY - 2010 DA - 2010// TI - Effect of aspirin and NSAIDs on risk and survival from colorectal cancer JO - Gut VL - 59 UR - https://doi.org/10.1136/gut.2009.203000 DO - 10.1136/gut.2009.203000 ID - Din2010 ER - TY - JOUR AU - Patrignani, P. AU - Capone, M. L. AU - Tacconelli, S. PY - 2008 DA - 2008// TI - NSAIDs and cardiovascular disease JO - Heart VL - 94 UR - https://doi.org/10.1136/hrt.2007.136002 DO - 10.1136/hrt.2007.136002 ID - Patrignani2008 ER - TY - JOUR AU - Colussi, D. AU - Brandi, G. AU - Bazzoli, F. AU - Ricciardiello, L. PY - 2013 DA - 2013// TI - Molecular pathways involved in colorectal cancer: implications for disease behavior and prevention JO - Int J Mol Sci VL - 14 UR - https://doi.org/10.3390/ijms140816365 DO - 10.3390/ijms140816365 ID - Colussi2013 ER - TY - JOUR AU - Carmona, F. J. AU - Esteller, M. PY - 2010 DA - 2010// TI - Epigenomics of human colon cancer JO - Mutat Res VL - 693 UR - https://doi.org/10.1016/j.mrfmmm.2010.07.007 DO - 10.1016/j.mrfmmm.2010.07.007 ID - Carmona2010 ER - TY - JOUR AU - Bardhan, K. AU - Liu, K. PY - 2013 DA - 2013// TI - Epigenetics and colorectal cancer pathogenesis JO - Cancers (Basel) VL - 5 UR - https://doi.org/10.3390/cancers5020676 DO - 10.3390/cancers5020676 ID - Bardhan2013 ER - TY - JOUR AU - Esteller, M. PY - 2007 DA - 2007// TI - Cancer epigenomics: DNA methylomes and histone-modification maps JO - Nat Rev Genet VL - 8 UR - https://doi.org/10.1038/nrg2005 DO - 10.1038/nrg2005 ID - Esteller2007 ER - TY - JOUR AU - Jones, P. A. AU - Baylin, S. B. PY - 2007 DA - 2007// TI - The epigenomics of cancer JO - Cell VL - 128 UR - https://doi.org/10.1016/j.cell.2007.01.029 DO - 10.1016/j.cell.2007.01.029 ID - Jones2007 ER - TY - JOUR AU - Cebola, I. AU - Peinado, M. A. PY - 2012 DA - 2012// TI - Epigenetic deregulation of the COX pathway in cancer JO - Prog Lipid Res VL - 51 UR - https://doi.org/10.1016/j.plipres.2012.02.005 DO - 10.1016/j.plipres.2012.02.005 ID - Cebola2012 ER - TY - JOUR AU - Harris, R. E. PY - 2007 DA - 2007// TI - Cyclooxygenase-2 (cox-2) and the inflammogenesis of cancer JO - Subcell Biochem VL - 42 UR - https://doi.org/10.1007/1-4020-5688-5_4 DO - 10.1007/1-4020-5688-5_4 ID - Harris2007 ER - TY - JOUR AU - Karnes, W. E. AU - Shattuck-Brandt, R. AU - Burgart, L. J. AU - DuBois, R. N. AU - Tester, D. J. AU - Cunningham, J. M. PY - 1998 DA - 1998// TI - Reduced COX-2 protein in colorectal cancer with defective mismatch repair JO - Cancer Res VL - 58 ID - Karnes1998 ER - TY - JOUR AU - Sinicrope, F. A. AU - Lemoine, M. AU - Xi, L. AU - Lynch, P. M. AU - Cleary, K. R. AU - Shen, Y. PY - 1999 DA - 1999// TI - Reduced expression of cyclooxygenase 2 proteins in hereditary nonpolyposis colorectal cancers relative to sporadic cancers JO - Gastroenterology VL - 117 UR - https://doi.org/10.1053/gast.1999.0029900350 DO - 10.1053/gast.1999.0029900350 ID - Sinicrope1999 ER - TY - JOUR AU - Frigola, J. AU - Muñoz, M. AU - Clark, S. J. AU - Moreno, V. AU - Capella, G. AU - Peinado, M. A. PY - 2005 DA - 2005// TI - Hypermethylation of the prostacyclin synthase (PTGIS) promoter is a frequent event in colorectal cancer and associated with aneuploidy JO - Oncogene VL - 24 UR - https://doi.org/10.1038/sj.onc.1208883 DO - 10.1038/sj.onc.1208883 ID - Frigola2005 ER - TY - JOUR AU - Luo, Y. AU - Wong, C. J. AU - Kaz, A. M. AU - Dzieciatkowski, S. AU - Carter, K. T. AU - Morris, S. M. PY - 2014 DA - 2014// TI - Differences in DNA methylation signatures reveal multiple pathways of progression from adenoma to colorectal cancer JO - Gastroenterology VL - 147 UR - https://doi.org/10.1053/j.gastro.2014.04.039 DO - 10.1053/j.gastro.2014.04.039 ID - Luo2014 ER - TY - JOUR AU - Rhee, I. AU - Bachman, K. E. AU - Park, B. H. AU - Jair, K. W. AU - Yen, R. W. AU - Schuebel, K. E. PY - 2002 DA - 2002// TI - DNMT1 and DNMT3b cooperate to silence genes in human cancer cells JO - Nature VL - 416 UR - https://doi.org/10.1038/416552a DO - 10.1038/416552a ID - Rhee2002 ER - TY - JOUR AU - Vogelstein, B. AU - Kinzler, K. W. PY - 2004 DA - 2004// TI - Cancer genes and the pathways they control JO - Nat Med VL - 10 UR - https://doi.org/10.1038/nm1087 DO - 10.1038/nm1087 ID - Vogelstein2004 ER - TY - JOUR AU - Hanahan, D. AU - Weinberg, R. A. PY - 2011 DA - 2011// TI - Hallmarks of cancer: the next generation JO - Cell VL - 144 UR - https://doi.org/10.1016/j.cell.2011.02.013 DO - 10.1016/j.cell.2011.02.013 ID - Hanahan2011 ER - TY - JOUR AU - Toyota, M. AU - Shen, L. AU - Ohe-Toyota, M. AU - Hamilton, S. R. AU - Sinicrope, F. A. AU - Issa, J. P. PY - 2000 DA - 2000// TI - Aberrant methylation of the cyclooxygenase 2 CpG island in colorectal tumors JO - Cancer Res VL - 60 ID - Toyota2000 ER - TY - JOUR AU - Maat, M. F. G. AU - Velde, C. J. H. AU - Umetani, N. AU - Heer, P. AU - Putter, H. AU - Hoesel, A. Q. PY - 2007 DA - 2007// TI - Epigenetic silencing of cyclooxygenase-2 affects clinical outcome in gastric cancer JO - J Clin Oncol VL - 25 UR - https://doi.org/10.1200/JCO.2006.09.8921 DO - 10.1200/JCO.2006.09.8921 ID - Maat2007 ER - TY - JOUR AU - Shoji, Y. AU - Takahashi, M. AU - Kitamura, T. AU - Watanabe, K. AU - Kawamori, T. AU - Maruyama, T. PY - 2004 DA - 2004// TI - Downregulation of prostaglandin E receptor subtype EP3 during colon cancer development JO - Gut VL - 53 UR - https://doi.org/10.1136/gut.2003.028787 DO - 10.1136/gut.2003.028787 ID - Shoji2004 ER - TY - JOUR AU - Gustafsson, A. AU - Hansson, E. AU - Kressner, U. AU - Nordgren, S. AU - Andersson, M. AU - Lonnroth, C. PY - 2007 DA - 2007// TI - Prostanoid receptor expression in colorectal cancer related to tumor stage, differentiation and progression JO - Acta Oncol VL - 46 UR - https://doi.org/10.1080/02841860701403061 DO - 10.1080/02841860701403061 ID - Gustafsson2007 ER - TY - JOUR AU - Kropotova, E. S. AU - Tychko, R. A. AU - Zinov'eva, O. L. AU - Zyrianova, A. F. AU - Khankin, S. L. AU - Cherkes, V. L. PY - 2010 DA - 2010// TI - Downregulation of AKR1B10 gene expression in colorectal cancer JO - Mol Biol (Mosk) VL - 44 UR - https://doi.org/10.1134/S0026893310020056 DO - 10.1134/S0026893310020056 ID - Kropotova2010 ER - TY - JOUR AU - Keshet, I. AU - Schlesinger, Y. AU - Farkash, S. AU - Rand, E. AU - Hecht, M. AU - Segal, E. PY - 2006 DA - 2006// TI - Evidence for an instructive mechanism of de novo methylation in cancer cells JO - Nat Genet VL - 38 UR - https://doi.org/10.1038/ng1719 DO - 10.1038/ng1719 ID - Keshet2006 ER - TY - JOUR AU - Tsujii, M. PY - 2013 DA - 2013// TI - Cyclooxygenase, cancer stem cells and DNA methylation play important roles in colorectal carcinogenesis JO - Digestion VL - 87 UR - https://doi.org/10.1159/000343898 DO - 10.1159/000343898 ID - Tsujii2013 ER - TY - JOUR AU - Xia, D. AU - Wang, D. AU - Kim, S. H. AU - Katoh, H. AU - DuBois, R. N. PY - 2012 DA - 2012// TI - Prostaglandin E2 promotes intestinal tumor growth via DNA methylation JO - Nat Med VL - 18 UR - https://doi.org/10.1038/nm.2608 DO - 10.1038/nm.2608 ID - Xia2012 ER - TY - JOUR AU - Nakanishi, M. AU - Perret, C. AU - Meuillet, E. J. AU - Rosenberg, D. W. PY - 2015 DA - 2015// TI - Non-cell autonomous effects of targeting inducible PGE2 synthesis during inflammation-associated colon carcinogenesis JO - Carcinogenesis VL - 36 UR - https://doi.org/10.1093/carcin/bgv004 DO - 10.1093/carcin/bgv004 ID - Nakanishi2015 ER - TY - JOUR AU - Wang, D. AU - DuBois, R. N. PY - 2004 DA - 2004// TI - Cyclooxygenase 2-derived prostaglandin E2 regulates the angiogenic switch JO - Proc Natl Acad Sci U S A VL - 101 UR - https://doi.org/10.1073/pnas.0307640100 DO - 10.1073/pnas.0307640100 ID - Wang2004 ER - TY - JOUR AU - Zuo, X. AU - Shureiqi, I. PY - 2013 DA - 2013// TI - Eicosanoid profiling in colon cancer: emergence of a pattern JO - Prostaglandins Other Lipid Mediat VL - 104-105 UR - https://doi.org/10.1016/j.prostaglandins.2012.08.004 DO - 10.1016/j.prostaglandins.2012.08.004 ID - Zuo2013 ER - TY - JOUR AU - Chandramouli, A. AU - Onyeagucha, B. C. AU - Mercado-Pimentel, M. E. AU - Stankova, L. AU - Shahin, N. A. AU - LaFleur, B. J. PY - 2012 DA - 2012// TI - MicroRNA-101 (miR-101) post-transcriptionally regulates the expression of EP4 receptor in colon cancers JO - Cancer Biol Ther VL - 13 UR - https://doi.org/10.4161/cbt.13.3.18874 DO - 10.4161/cbt.13.3.18874 ID - Chandramouli2012 ER - TY - JOUR AU - Katoh, H. AU - Hosono, K. AU - Ito, Y. AU - Suzuki, T. AU - Ogawa, Y. AU - Kubo, H. PY - 2010 DA - 2010// TI - COX-2 and prostaglandin EP3/EP4 signaling regulate the tumor stromal proangiogenic microenvironment via CXCL12-CXCR4 chemokine systems JO - Am J Pathol VL - 176 UR - https://doi.org/10.2353/ajpath.2010.090607 DO - 10.2353/ajpath.2010.090607 ID - Katoh2010 ER - TY - JOUR AU - Kubo, H. AU - Hosono, K. AU - Suzuki, T. AU - Ogawa, Y. AU - Kato, H. AU - Kamata, H. PY - 2010 DA - 2010// TI - Host prostaglandin EP3 receptor signaling relevant to tumor-associated lymphangiogenesis JO - Biomed Pharmacother VL - 64 UR - https://doi.org/10.1016/j.biopha.2009.04.039 DO - 10.1016/j.biopha.2009.04.039 ID - Kubo2010 ER - TY - JOUR AU - Bishehsari, F. AU - Mahdavinia, M. AU - Vacca, M. AU - Malekzadeh, R. AU - Mariani-Costantini, R. PY - 2014 DA - 2014// TI - Epidemiological transition of colorectal cancer in developing countries: environmental factors, molecular pathways, and opportunities for prevention JO - World J Gastroenterol VL - 20 UR - https://doi.org/10.3748/wjg.v20.i20.6055 DO - 10.3748/wjg.v20.i20.6055 ID - Bishehsari2014 ER - TY - JOUR AU - Barrow, T. M. AU - Michels, K. B. PY - 2014 DA - 2014// TI - Epigenetic epidemiology of cancer JO - Biochem Biophys Res Commun VL - 455 UR - https://doi.org/10.1016/j.bbrc.2014.08.002 DO - 10.1016/j.bbrc.2014.08.002 ID - Barrow2014 ER - TY - JOUR AU - Coppede, F. PY - 2014 DA - 2014// TI - The role of epigenetics in colorectal cancer JO - Expert Rev Gastroenterol Hepatol VL - 8 UR - https://doi.org/10.1586/17474124.2014.924397 DO - 10.1586/17474124.2014.924397 ID - Coppede2014 ER - TY - JOUR AU - Ogino, S. AU - Lochhead, P. AU - Chan, A. T. AU - Nishihara, R. AU - Cho, E. AU - Wolpin, B. M. PY - 2013 DA - 2013// TI - Molecular pathological epidemiology of epigenetics: emerging integrative science to analyze environment, host, and disease JO - Mod Pathol VL - 26 UR - https://doi.org/10.1038/modpathol.2012.214 DO - 10.1038/modpathol.2012.214 ID - Ogino2013 ER - TY - JOUR AU - Sanz-Pamplona, R. AU - Berenguer, A. AU - Cordero, D. AU - Mollevi, D. G. AU - Crous-Bou, M. AU - Sole, X. PY - 2014 DA - 2014// TI - Aberrant gene expression in mucosa adjacent to tumor reveals a molecular crosstalk in colon cancer JO - Mol Cancer VL - 13 UR - https://doi.org/10.1186/1476-4598-13-46 DO - 10.1186/1476-4598-13-46 ID - Sanz-Pamplona2014 ER - TY - JOUR AU - Worm, J. AU - Aggerholm, A. AU - Guldberg, P. PY - 2001 DA - 2001// TI - In-tube DNA methylation profiling by fluorescence melting curve analysis JO - Clin Chem VL - 47 ID - Worm2001 ER -