Skip to main content

Table 4 The 41 CpGs that had the same direction of effect with eczema in both F1 and F2 generations based on log-linear models

From: Identifying CpG sites associated with eczema via random forest screening of epigenome-scale DNA methylation

CpGs

F1-Risk Ratio

95 % CI-F1

F2-risk ratio

95 % CI-F2

Gene

cg00193668

17.29

2.90, 102.87

4.86

0.89, 26.4

HINT2

cg04850479a

15.19

3.07, 75.17

6.82

1.52, 30.6

PROZ

cg02641560

14.50

3.39, 62.65

1.33

0.13, 12.8

RCAN3

cg05839818

13.02

2.34, 72.26

1.3

0.13, 12.1

 

cg05411056

9.73

2.64, 35.81

5.61

1.44, 21.85

 

cg02077766

9.60

2.14, 43.07

1.29

0.38, 4.33

PTCRA

cg00667315

7.66

1.88, 31.21

1.25

0.19, 8.0

 

cg00900242

6.86

1.26, 37.20

6.04

0.75, 48.6

 

cg02583247

6.61

2.05, 21.33

1.27

0.26, 6.10

FGF6

cg01802073

6.10

1.40, 26.43

1.43

0.24, 8.61

CGRRF1

cg14839837

5.90

1.63, 21.39

2.94

0.73, 11.7

ARHGEF10

cg00354884

5.77

1.95, 17.03

1.8

0.59, 6.03

ABR

cg00158434

5.43

1.75, 16.78

2.47

0.52, 11.5

ALMS1P

cg03049303

4.73

1.44, 15.57

4.61

0.77, 27.4

C10orf76

cg24303123

4.68

1.73, 12.65

1.49

0.50, 4.46

RIPK1

cg11570082

4.46

1.85, 10.71

2.56

0.58, 11.2

 

cg02237186

4.26

1.24, 14.63

2.89

0.16, 51.1

RRM2

cg02654265

3.92

1.56, 9.87

0.29

0.05, 1.52

 

cg00369908

3.65

1.34, 9.92

4.05

0.75, 21.6

ING4

cg00722180

3.64

1.22, 0.85

2.84

0.63, 12.7

RBM25

cg02433979

2.91

1.35, 6.27

1.17

0.37, 3.68

 

cg00035220

2.62

1.19, 5.72

1.18

0.34, 4.03

PTPRN2

cg00252472

2.62

1.27, 5.40

1.22

0.44, 3.38

 

cg00306063

2.59

1.12, 5.97

2.12

0.48, 9.19

LOC100129066

cg00742851

2.23

1.16, 4.28

1.26

0.45, 3.48

LRRN1

cg02203881

2.07

1.07, 4.00

1.67

0.46, 6.02

PLA2G4D

cg00576402

0.57

0.35, 0.92

0.76

0.28, 2.07

PTPN12

cg01560119

0.41

0.21, 0.80

0.79

0.37, 1.68

SETDB2

cg01651499

0.37

0.16, 0.85

0.41

0.12, 1.34

GUCY1A3

cg02098905

0.35

0.16, 0.76

0.41

0.14, 1.12

 

cg04797820

0.33

0.17, 0.64

0.93

0.31, 2.76

GLT1D1

cg00247571

0.31

0.13, 0.75

0.89

0.26, 2.50

 

cg00071869

0.30

0.13, 0.70

0.77

0.12, 4.88

ATP1B3

cg00797821

0.29

0.10, 0.82

0.36

0.06, 2.12

 

cg01158447

0.24

0.09, 0.60

0.35

0.11, 1.14

SLC40A1

cg00077547

0.21

0.06, 0.70

0.91

0.25, 3.24

TMEM26

cg04980849

0.21

0.07, 0.60

0.57

0.16, 1.96

LOC145663; GATM

cg00050654

0.19

0.07, 0.51

0.71

0.20, 2.43

 

cg20077343

0.19

0.06, 0.58

0.25

0.03, 1.83

MUC6

cg17602756

0.14

0.03, 0.64

0.26

0.05, 1.39

SQSTM1

cg01427769a

0.13

0.03, 0.46

0.09

0.02, 0.36

NEU1

  1. aCpG sites significantly associated with eczema in both generations. For cg04850479, the P values are 0.0006 in the F1 generation and 0.0121 in the F2 generation, and for cg01427769, the P values are 0.0015 and 0.0007, respectively
Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us