Table 3 Associations between selected miRNAs (∆Ct at baseline) and MADRS-S for the whole cohort, as determined using linear regression
From: Circulating microRNA-144-5p is associated with depressive disorders
Univariate analysis | Adjusted analysis | |||||
|---|---|---|---|---|---|---|
β | p value | 95 % CI | β | p value | 95 % CI | |
miR-144-5p (n = 166) | ||||||
MADRS-S at baseline | −0.02 | 0.009 | −0.03; −0.005 | −0.02 | 0.008 | −0.03; −0.005 |
Sex (female vs. male) | −0.34 | 0.03 | −0.64; −0.04 | |||
Age | 0.005 | 0.28 | −0.004; 0.01 | |||
miR-29a-5p (n = 159)a | ||||||
MADRS-S at baseline | 0.02 | 0.04 | 0.0004; 0.03 | 0.01 | 0.06 | −0.0005; 0.03 |
Sex (female vs. male) | −0.007 | 0.97 | −0.35; 0.34 | |||
Age | −0.01 | 0.04 | −0.02; −0.0007 | |||
miR-29b-2-5p (n = 159)a | ||||||
MADRS-S at baseline | 0.004 | 0.62 | −0.01; 0.02 | 0.004 | 0.61 | −0.01; 0.02 |
Sex (female vs. male) | −0.18 | 0.30 | −0.53; 0.16 | |||
Age | 0.005 | 0.39 | −0.006; 0.01 | |||
miR-30a-5p (n = 159)a | ||||||
MADRS-S at baseline | 0.002 | 0.73 | −0.01; 0.02 | 0.003 | 0.68 | −0.01; 0.02 |
Sex (female vs. male) | 0.24 | 0.14 | −0.07; 0.55 | |||
Age | 0.0006 | 0.90 | −0.009; 0.01 | |||
miR-92b-3p (n = 166)a | ||||||
MADRS-S at baseline | 0.01 | 0.11 | −0.002; 0.02 | 0.01 | 0.12 | −0.002; 0.02 |
Sex (female vs. male) | 0.04 | 0.78 | −0.23; 0.30 | |||
Age | −0.003 | 0.51 | −0.01; 0.005 | |||