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Table 2 Clinical, biochemical, and serological characteristics of PBC patients

From: DNA methylation profiling of the X chromosome reveals an aberrant demethylation on CXCR3 promoter in primary biliary cirrhosis

 

PBC patients

Healthy controls

(n = 30)

(n = 30)

Mean age (years, range)

64 (44–87)

60 (42–79)

Females (n, %)

30 (100 %)

30 (100 %)

AMA positivity (n, %)

28 (93 %)

n.a.

Liver cirrhosis (n, %)

4 (13 %)

n.a.

Total bilirubin (mg/dl) (n.v. <1.0)

0.64 ± 0.39

0.73 ± 0.18

Alkaline phosphatase (IU/l) (n.v. <279)

152.3 ± 207.3

168 ± 24

Alanine aminotransferase (U/l) (n.v. <50)

33 ± 26

32 ± 9

Albumin (g/dl) (n.v. >3.5)

4.33 ± 0.86

4.68 ± 0.03

Length of follow-up (months, range)

34 (14–56)

n.a.

Therapy with UDCA (n, %)

28 (93 %)

n.a.

Liver biopsy (n, %)

21 (72 %)

n.a.

  1. Mean values ± standard deviation unless otherwise stated
  2. n.a. not applicable, n.v. normal value