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Fig. 2 | Clinical Epigenetics

Fig. 2

From: MicroRNA expression profiling predicts clinical outcome of carboplatin/paclitaxel-based therapy in metastatic melanoma treated on the ECOG-ACRIN trial E2603

Fig. 2

Clustergram of genes whose expression was inversely correlated with miR-659-3p expression in our dataset (a). Target predictions of miR-659-3p identified utilizing mirConnX software for network inference (b). Several oncogenes known to be involved in melanoma disease mechanisms are highlighted in gold. Genes are represented by squares, miRNAs by triangles, and transcription factors by circles. Left panel, anti-correlated genes; center panel, genes in the KEGG melanoma pathway; top right corner, other cancer-related genes

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Clinical Epigenetics

ISSN: 1868-7083

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