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Table 1 Characteristics of study population

From: Tobacco smoking is associated with methylation of genes related to coronary artery disease

  Total Current smokers Former smokers Never smokers p-valuea
N 724 195 319 210  
Age (years) 59.9 (8.2) 58.1 (6.7) 61.5 (8.6) 59.2 (8.4) 0.15
Sex (male) 334 (46 %) 98 (50 %) 155 (49 %) 78 (37 %) 0.008
BMI (kg/m2) 27.6 (4.6) 26.8 (4.3) 28.0 (4.5) 27.7 (4.9) 0.05
Proportion CD8+ T-cellsb 0.09 (0.05) 0.10 (0.05) 0.09 (0.06) 0.10 (0.05) 0.81
Proportion CD4+ T-cellsb 0.26 (0.08) 0.27 (0.07) 0.26 (0.08) 0.26 (0.08) 0.33
Proportion NK cellsb 0.14 (0.06) 0.11 (0.06) 0.14 (0.06) 0.14 (0.06) <0.001
Proportion B-cellsb 0.10 (0.04) 0.10 (0.04) 0.10 (0.03) 0.10 (0.04) 0.59
Proportion monocytesb 0.08 (0.03) 0.08 (0.03) 0.08 (0.03) 0.08 (0.03) 0.55
Proportion granulocytesb 0.37 (0.11) 0.38 (0.11) 0.37 (0.12) 0.37 (0.11) 0.12
Nr. erythrocytes (109/L) 4.90 (0.37) 4.86 (0.36) 4.93 (0.37) 4.88 (0.38) 0.67
Nr. platelets (109/L) 283.8 (63.9) 293.2 (69.3) 280.2 (61.0) 280.4 (62.4) 0.05
Fasting (yes)c 717 (99 %) 192 (99 %) 315 (99 %) 210 (100 %) 0.07
Alcohol (g/day) 18.2 (11.3) 19.3 (12.8) 18.9 (11.5) 16.0 (8.9) 0.002
RNA quality score 8.38 (0.51) 8.36 (0.50) 8.39 (0.49) 8.38 (0.54) 0.66
Type 2 diabetes mellitus 53 (7.3 %) 7 (3.6 %) 34 (10.6 %) 12 (5.7 %) 0.31
Total cholesterol (mmol/L) 5.6 (1.3) 5.6 (1.1) 5.6 (1.5) 5.6 (1.1) 0.88
Triglycerides (mmol/L) 1.49 (0.87) 1.68 (1.14) 1.43 (0.68) 1.39 (0.80) 0.005
Systolic blood pressure (mmHg) 135.7 (61.7) 132.3 (61.7) 137.5 (64.3) 136.3 (57.6) 0.50
Diastolic blood pressure (mmHg) 84.9 (63.3) 83.5 (61.7) 85.6 (66.7) 85.1 (59.7) 0.79
  1. Data are mean (SD) or n (%)
  2. aCurrent versus never
  3. bHouseman-estimated white blood cell proportions
  4. cThe subjects who provided blood in fasting condition