Figure 7From: Coordinated epigenetic remodelling of transcriptional networks occurs during early breast carcinogenesisThe FOXA1 locus is specifically methylated in basal-like tumours in the TCGA HM450 cohort. Two regions (regions A and B) containing four vHMEC DMRs that flank (but not cover) the FOXA1 promoter exhibit increased methylation specific to basal-like tumours (region A AUC > 0.84 and region B AUC > 0.84).Back to article page