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Table 1 Clinical and biochemical characteristics of HCC patients

From: DNA methylation and gene expression profiles show novel regulatory pathways in hepatocellular carcinoma

Subject Age (years) Alcohol (units) a Smoking Child-Pugh score HBsAg HCVAb Hb (g/dL) MCV (fL) IgA (g/L) GGT (U/L) CHE (U/L) AST (U/L) ALT (U/L) aFP (mg/L)
1 66 >20 yes A6 Neg Neg 12.1 88.0 2.22 67 4,138 25 57 5,871
2 70 6 yes A5 Neg Neg 12.0 69.1 0.91 32 4,606 23 37 411
3 66 16 yes A5 Neg Neg 15.6 89.9 4.08 48 4,624 30 33 967
4 82 11 yes A5 Neg Neg 11.2 88.8 1.66 43 7,353 29 28 62
5 68 5 no A5 Neg Neg 16.0 98.1 3.98 52 7,856 25 29 190
6 60 6 yes A5 Neg Neg 13.8 98.6 1.60 223 3,564 38 51 5
7 75 4 yes A5 Neg Neg 13.7 90.3 3.28 30 7,225 28 15 431
8 71 10 yes A5 Neg Neg 13.3 91.4 1.56 88 8,430 24 29 21
  1. a1 unit is defined as 12 g of ethanol = 125-ml wine or 330-ml beer or 40-ml spirit.
  2. Abbreviations: HBV Ag, hepatitis B virus antigen ; HCVAb, hepatitis C virus antibody; Hb, hemoglobin; MCV, mean corpuscolar volume; IgA, immunoglobulin fraction A; GGT, gamma-glutamyl transpeptidase; CHE, cholinesterase; AST, aspartate transaminase; ALT, alanine transaminase; aFP, alphafetoprotein.
  3. Alcohol drinking defined as ≥36 g ethanol/day for males and ≥24 g ethanol/day for females.
  4. Reference values: Hb (g/dl) 13.5 to 16; MCV (fl) 86 to 98; IgA (g/L) 0.7 to 4.0; GGT (U/l) <50; CHE (U/l) 4,650 to 14,400; AST (U/l) 8 to 50; ALT (U/l) 8 to 45; aFP (mg/L) <7.