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Table 1 Enriched KEGG pathways

From: Genome-wide blood DNA methylation alterations at regulatory elements and heterochromatic regions in monozygotic twins discordant for obesity and liver fat

KEGG pathway Score P value FDR CTEA score CTEA P value CTEA FDR
BMI discordant       
4977 Vitamin digestion and absorption −0.23 0.002 0.098 −0.23 0.002 0.065
4614 Renin-angiotensin system −0.23 0.003 0.098 −0.22 0.009 0.195
eLF group       
260 Glycine, serine and threonine metabolism −0.19 <0.001 <0.001 −0.16 0.001 0.033
340 Histidine metabolism −0.13 0.002 0.052 −0.12 0.005 0.065
4977 Vitamin digestion and absorption −0.19 0.003 0.052 −0.15 0.020 0.130
4614 Renin-angiotensin system −0.22 0.004 0.052 −0.24 0.001 0.033
300 Lysine biosynthesis −0.48 0.004 0.052 −0.44 0.003 0.065
780 Biotin metabolism −0.61 0.006 0.056 −0.64 0.009 0.084
920 Sulfur metabolism −0.29 0.006 0.056 −0.29 0.006 0.065
591 Linoleic acid metabolism 0.36 0.001 0.065 0.49 <0.001 <0.001
830 Retinol metabolism −0.11 0.011 0.089 −0.19 0.005 0.065
  1. 1,000 permutations were performed with no probe number cutoffs. CTEA cell-type estimate adjusted.