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Figure 3 | Clinical Epigenetics

Figure 3

From: Genome-wide blood DNA methylation alterations at regulatory elements and heterochromatic regions in monozygotic twins discordant for obesity and liver fat

Figure 3

CGIs underrepresented and open seas overrepresented among the differentially methylated CpGs. Bar plot shows the proportions of the differentially methylated CpGs at CGIs, shores, shelves, and open sea and the P values denote which of the CpG categories are over- or underrepresented among the differentially methylated CpGs (n = 1,236) in the eLF group. Fisher’s exact test was used to generate P values for each group to see if they are under- or overrepresented among the 1,236 CpGs. Open sea, isolated CpGs outside any CGIs; shelves, 2 to 4 kb from CGI; CGI shores, <2 kb from CGI.

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