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Table 1 Main demographic and clinical characteristics of the study population

From: Differences in DNA methylation profile of Th1 and Th2 cytokine genes are associated with tolerance acquisition in children with IgE-mediated cow’s milk allergy

  Subjects with CMA at diagnosis Subjects outgrown CMA Healthy subjects
  Group 1 Group 2 Group 3
N 10 20 10
Male, n (%) 7 (70) 13 (65) 4 (40)
Age, m (SD) 5.5 (0.7) 16.9 (0.9) 9 (4)
Body weight, kg (SD) 7.385 (964.7) 12.160 (720.9) 8.075 (3193.5)
Spontaneous delivery, n (%) 5 (50) 5 (25) 4 (40)
Breastfeeding, ≤8 weeks, n (%) 10 (100) 20 (100) 10 (100)
Symptoms at the CMA onset    
    Gastrointestinal, n (%) 4 (40) 8 (40) -
    Cutaneous, n (%) 8 (80) 15 (75) -
    Respiratory, n (%) 1 (10) 6 (30) -
Total serum IgE, kU/l (SD) 260.6 (230.9) 193.1 (209.5) 0.2 (0.1)
nBos d 4, kUA/l (SD) 6 (11.2) 1.9 (3) -
nBos d 5, kUA/l (SD) 4.5 (7.1) 2 (3) -
nBos d 6, kUA/l (SD) 5.4 (8.7) 1.4 (2.5) -
nBos d 8, kUA/l (SD) 22.7 (39.2) 0.9 (1.9) -
Lactoferrin, kUA/l (SD) 2 (6.1) 0 -