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Table 1 Main demographic and clinical characteristics of the study population

From: Differences in DNA methylation profile of Th1 and Th2 cytokine genes are associated with tolerance acquisition in children with IgE-mediated cow’s milk allergy

 

Subjects with CMA at diagnosis

Subjects outgrown CMA

Healthy subjects

 

Group 1

Group 2

Group 3

N

10

20

10

Male, n (%)

7 (70)

13 (65)

4 (40)

Age, m (SD)

5.5 (0.7)

16.9 (0.9)

9 (4)

Body weight, kg (SD)

7.385 (964.7)

12.160 (720.9)

8.075 (3193.5)

Spontaneous delivery, n (%)

5 (50)

5 (25)

4 (40)

Breastfeeding, ≤8 weeks, n (%)

10 (100)

20 (100)

10 (100)

Symptoms at the CMA onset

   

    Gastrointestinal, n (%)

4 (40)

8 (40)

-

    Cutaneous, n (%)

8 (80)

15 (75)

-

    Respiratory, n (%)

1 (10)

6 (30)

-

Total serum IgE, kU/l (SD)

260.6 (230.9)

193.1 (209.5)

0.2 (0.1)

nBos d 4, kUA/l (SD)

6 (11.2)

1.9 (3)

-

nBos d 5, kUA/l (SD)

4.5 (7.1)

2 (3)

-

nBos d 6, kUA/l (SD)

5.4 (8.7)

1.4 (2.5)

-

nBos d 8, kUA/l (SD)

22.7 (39.2)

0.9 (1.9)

-

Lactoferrin, kUA/l (SD)

2 (6.1)

0

-