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Figure 1 | Clinical Epigenetics

Figure 1

From: Differences in DNA methylation profile of Th1 and Th2 cytokine genes are associated with tolerance acquisition in children with IgE-mediated cow’s milk allergy

Figure 1

DNA methylation rate of the IL-4, IL-5, IL-10, and INF-γ genes (A, B, C, D, respectively) observed in the study population. The rate of promoter gene methylation of IL-4 and IL-5 was lower and IL-10 and IFN-γ was higher in group 1 than group 3. Group 2 presented a methylation rate similar to that observed in group 3. (group 3 vs group 1: coefficient −0.151, SE 0.058; P < 0.0001; group 1 vs group 2: coefficient 0.542, SE 0.2518; P < 0.0001).

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