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Table 1 Correlation between the percent methylation of each studied CG and child height ( N = 216 )

From: The IGF1 P2 promoter is an epigenetic QTL for circulating IGF1 and human growth

  Height (SDS)
Discovery cohort Replication cohort Total
R P R P R P
P1 promoter CG-1044 0.02 1 0.02 1 0.03 1
CG-960 0.05 1 0.06 1 0.06 1
CG-919 0.02 1 −0.13 1 0.04 1
CG-631 −0.04 1 −0.04 1 −0.09 1
CG-611 −0.25 0.1 −0.48 2.2.10 −5 −0.39 4.10 −7
CG-491 −0.06 1 −0.31 0.03 −0.10 1
CG-414 0.00 1 −0.19 0.4 0.09 1
CG-308 0.02 1 0.02 1 0.00 1
CG-225 0.08 1 0.012 1 −0.10 1
P2 promoter CG-232 −0.08 1 −0.28 0.03 −0.21 0.01
CG-224 −0.32 10 −2 −0.17 0.7 −0.24 0.003
CG-218 −0.36 10 −3 −0.30 0.02 −0.33 1.2.10 −5
CG-207 −0.35 2.10 −3 −0.12 1 −0.24 4.10 −3
CG-137 −0.30 10 −2 −0.40 1.9.10 −4 −0.36 4.10 −7
CG-108 −0.25 0.10 −0.19 0.5 −0.23 0.12
Average* −0.31 0.007 −0.27 0.004 −0.3 7.10 −5
CG-77 −0.09 1 −0.04 1 −0.04 1
CG + 97 −0.08 1 −0.03 1 0.07 1
  1. *Values for the averaged 6 CGs from −108 to −232. To account for multiple CG testing, we used Bonferroni correction of the P values. P values greater than 1 are equated to 1.
  2. Italicized letters and numbers indicate significant correlation.