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Table 1 Correlation between the percent methylation of each studied CG and child height ( N = 216 )

From: The IGF1 P2 promoter is an epigenetic QTL for circulating IGF1 and human growth

 

Height (SDS)

Discovery cohort

Replication cohort

Total

R

P

R

P

R

P

P1 promoter

CG-1044

0.02

1

0.02

1

0.03

1

CG-960

0.05

1

0.06

1

0.06

1

CG-919

0.02

1

−0.13

1

0.04

1

CG-631

−0.04

1

−0.04

1

−0.09

1

CG-611

−0.25

0.1

−0.48

2.2.10 −5

−0.39

4.10 −7

CG-491

−0.06

1

−0.31

0.03

−0.10

1

CG-414

0.00

1

−0.19

0.4

0.09

1

CG-308

0.02

1

0.02

1

0.00

1

CG-225

0.08

1

0.012

1

−0.10

1

P2 promoter

CG-232

−0.08

1

−0.28

0.03

−0.21

0.01

CG-224

−0.32

10 −2

−0.17

0.7

−0.24

0.003

CG-218

−0.36

10 −3

−0.30

0.02

−0.33

1.2.10 −5

CG-207

−0.35

2.10 −3

−0.12

1

−0.24

4.10 −3

CG-137

−0.30

10 −2

−0.40

1.9.10 −4

−0.36

4.10 −7

CG-108

−0.25

0.10

−0.19

0.5

−0.23

0.12

Average*

−0.31

0.007

−0.27

0.004

−0.3

7.10 −5

CG-77

−0.09

1

−0.04

1

−0.04

1

CG + 97

−0.08

1

−0.03

1

0.07

1

  1. *Values for the averaged 6 CGs from −108 to −232. To account for multiple CG testing, we used Bonferroni correction of the P values. P values greater than 1 are equated to 1.
  2. Italicized letters and numbers indicate significant correlation.
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Clinical Epigenetics

ISSN: 1868-7083

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