From: Effects of phthalate exposure on asthma may be mediated through alterations in DNA methylation
Asthma | Non-asthma | Subjects | OR | Adjusted OR b | |
---|---|---|---|---|---|
( N = 56) | ( N = 200) | ( N = 256) | (95% CIs) | (95% CIs) | |
Lower methylated TNFα 5′CGIa | 35(62.5) | 93(46.5) | 128(50.0) | 1.92(1.04 to 3.52)* | 2.15(1.01 to 4.62)* |
Higher methylated | 21(37.5) | 107(53.5) | 128(50.0) | 1 | 1 |