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Table 1 Comparison of the clinical and demographic factors between mild and severe NALFD cohorts

From: Differential DNA methylation of genes involved in fibrosis progression in non-alcoholic fatty liver disease and alcoholic liver disease

  NAFLD (mild fibrosis) F0 to F2 ( n = 8) NAFLD (severe fibrosis) F3 to F4 ( n = 9) Statistical significance
Age, mean (95% CI) 51.88 (40.43 to 63.32) 60.56 (54.50 to 66.61) ns
Male sex (%) 8 (100%) 9 (100%) ns
AST (IU/L) (95% CI) 45.38 (27.69 to 63.06) 43.86 (32.92 to 54.79) ns
ALT (IU/L) (95% CI) 79.75 (39.51 to 120) 45.56 (30.5 to 60.96) P = 0.04
BMI (kg/m2) 35 (30 to 43.2) 36 (30 to 46) ns
Cholesterol (mmol/L) 5.2 (3 to 7) 4.0 (2.7 to 5.5) ns
Triglycerides (mmol/L) 5.8 (2 to 12.5) 2.2 (0.8 to 4.7) P = 0.01
HDL cholesterol (mmol/L) 0.9 (0.6 to 1.2) 1.1 (0.7 to 1.6) ns
LDL cholesterol (mmol/L) 3.8 (2.1 to 6.2) 2.6 (1.5 to 3.9) ns
Total/HDL ratio 6.1 (3.3 to 9.5) 3.9 (2.1 to 6.1) ns
Steatosis    
0 (<5%) - 1  
  1 (5% to 33%) 1 8  
  2 (33% to 66%) 5 -  
  3 (66%<) 2   
Inflammation    
  0 2 1  
  1 4 3  
  2 2 5  
  3    
Ballooning    
  0 1 2  
  1 7 3  
  2 - 4  
Fibrosis    
  0 - -  
  1 7 -  
  2 2 -  
  3 - 4  
  4 - 5