Table 1 Comparison of the clinical and demographic factors between mild and severe NALFD cohorts
NAFLD (mild fibrosis) F0 to F2 ( n = 8) | NAFLD (severe fibrosis) F3 to F4 ( n = 9) | Statistical significance | |
|---|---|---|---|
Age, mean (95% CI) | 51.88 (40.43 to 63.32) | 60.56 (54.50 to 66.61) | ns |
Male sex (%) | 8 (100%) | 9 (100%) | ns |
AST (IU/L) (95% CI) | 45.38 (27.69 to 63.06) | 43.86 (32.92 to 54.79) | ns |
ALT (IU/L) (95% CI) | 79.75 (39.51 to 120) | 45.56 (30.5 to 60.96) | P = 0.04 |
BMI (kg/m2) | 35 (30 to 43.2) | 36 (30 to 46) | ns |
Cholesterol (mmol/L) | 5.2 (3 to 7) | 4.0 (2.7 to 5.5) | ns |
Triglycerides (mmol/L) | 5.8 (2 to 12.5) | 2.2 (0.8 to 4.7) | P = 0.01 |
HDL cholesterol (mmol/L) | 0.9 (0.6 to 1.2) | 1.1 (0.7 to 1.6) | ns |
LDL cholesterol (mmol/L) | 3.8 (2.1 to 6.2) | 2.6 (1.5 to 3.9) | ns |
Total/HDL ratio | 6.1 (3.3 to 9.5) | 3.9 (2.1 to 6.1) | ns |
Steatosis | |||
0 (<5%) | - | 1 | |
1 (5% to 33%) | 1 | 8 | |
2 (33% to 66%) | 5 | - | |
3 (66%<) | 2 | ||
Inflammation | |||
0 | 2 | 1 | |
1 | 4 | 3 | |
2 | 2 | 5 | |
3 | |||
Ballooning | |||
0 | 1 | 2 | |
1 | 7 | 3 | |
2 | - | 4 | |
Fibrosis | |||
0 | - | - | |
1 | 7 | - | |
2 | 2 | - | |
3 | - | 4 | |
4 | - | 5 |