Skip to main content

Table 3 CpG sites and genes of interest (genes with significant TSS200)

From: Genome-scale hypomethylation in the cord blood DNAs associated with early onset preeclampsia

Gene

Case

Control

IPA network

CCL22

0.164

0.096

Inflammatory response, cellular function and maintenance, respiratory disease

CD86

1.014

0.875

Inflammatory response, cellular function and maintenance, respiratory disease

CFLAR

1.366

1.161

Inflammatory response, cellular function and maintenance, respiratory disease

FPR2

0.638

0.363

Inflammatory response, cellular function and maintenance, respiratory disease

IL19

1.545

1.727

Inflammatory response, cellular function and maintenance, respiratory disease

MPO

0.588

0.388

Inflammatory response, cellular function and maintenance, respiratory disease

NLRC4

0.696

0.471

Inflammatory response, cellular function and maintenance, respiratory disease

OSCAR

1.687

1.135

Inflammatory response, cellular function and maintenance, respiratory disease

PTK6

2.161

1.752

Inflammatory response, cellular function and maintenance, respiratory disease

TNFSF4

0.254

0.187

Inflammatory response, cellular function and maintenance, respiratory disease

TRAF3IP2

3.943

3.651

Inflammatory response, cellular function and maintenance, respiratory disease

CCL23

0.655

0.477

Cellular development, cellular growth and proliferation, hematological system development and function

CCR6

3.000

3.299

Cellular development, cellular growth and proliferation, hematological system development and function

FAS

1.226

0.865

Cellular development, cellular growth and proliferation, hematological system development and function

FASLG

1.294

1.566

Cellular development, cellular growth and proliferation, hematological system development and function

NCF4

0.766

0.532

Cellular development, cellular growth and proliferation, hematological system development and function

PIK3R1

3.526

3.337

Cellular development, cellular growth and proliferation, hematological system development and function

ADORA2A a

1.879

1.077

Cell-to-cell signaling and interaction, hematological system development and function, immune cell trafficking

CD226

1.384

1.554

Cell-to-cell signaling and interaction, hematological system development and function, immune cell trafficking

ELANE

1.190

0.876

Cell-to-cell signaling and interaction, hematological system development and function, immune cell trafficking

EMR1

1.146

0.699

Cell-to-cell signaling and interaction, hematological system development and function, immune cell trafficking

FCER1G

0.176

0.105

Cell-to-cell signaling and interaction, hematological system development and function, immune cell trafficking

IL27

1.105

0.856

Cell-to-cell signaling and interaction, hematological system development and function, immune cell trafficking

IL18BP

5.765

4.816

Cell-to-cell signaling and interaction, hematological system development and function, immune cell trafficking

IL1RN

1.998

2.652

Cell-to-cell signaling and interaction, hematological system development and function, immune cell trafficking

ISG20

0.140

0.079

Cell-to-cell signaling and interaction, hematological system development and function, immune cell trafficking

PCK1

1.725

2.310

Cell-to-cell signaling and interaction, hematological system development and function, immune cell trafficking

PRTN3

0.911

0.637

Cell-to-cell signaling and interaction, hematological system development and function, immune cell trafficking

MIR24-2

1.044

0.801

Inflammatory response, cellular development, tissue development

MIR1204

1.451

1.630

Inflammatory response, cellular development, tissue development

MIR21

1.736

1.911

Cell-to-cell signaling and interaction, hematological system development and function, immune cell trafficking

MIR27A

0.279

0.217

Inflammatory response, cellular development, tissue development

  1. aThis gene has significant methylation changes in the TSS200 related to gestational age, by comparing to the results of Cruickshank et al. [32].