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Table 2 Association of the SLC30A8 genetic polymorphisms with type 2 diabetes and diabetic nephropathy in a Malay population

From: Increased DNA methylation of the SLC30A8 gene promoter is associated with type 2 diabetes in a Malay population

SNP ID Group N Genotypes RAF P value Odds ratio
rs13266634    CC CT TT    
NGT 438 153 202 83 0.580 0.053 1.200 (0.997 to 1.443)
All T2Da 506 208 215 83 0.620
T2D-DN 236 90 107 39 0.608 0.098 1.313 (0.950 to 1.815)
T2D + DN 123 59 47 17 0.670
rs11558471    AA AG GG    
NGT 441 139 209 93 0.552 0.002 1.334 (1.110 to 1.602)
All T2Da 509 204 225 80 0.620
T2D-DN 237 87 107 43 0.593 0.041 1.399 (1.013 to 1.932)
T2D + DN 123 57 51 15 0.671
  1. Tests were conducted with an additive model.
  2. NGT normal glucose tolerance, T2D type 2 diabetes, DN diabetic nephropathy, RAF risk allele frequency.
  3. aThe patients with microalbuminuria were included.