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Table 3 MetS status on aging rate in known MetS genes

From: An epigenetic map of age-associated autosomal loci in northern European families at high risk for the metabolic syndrome

CpG site P age Beta (age, all) Beta (age, no MetS) Beta (age, MetS) P diff Chr Position (bp) Gene Gene region
cg06117072 1.62 × 10−15 0.030 0.027 −0.010 0.004 6 50899344 TFAP2B Body
cg04926134 5.73 × 10−14 0.029 0.031 −0.006 0.005 2 165186498 GRB14 First exon
cg14683125 1.04 × 10−16 0.028 0.023 −0.005 0.023 8 126510565 TRIB1 TSS1500
cg22697325 2.64 × 10−18 −0.031 −0.020 0.004 0.046 1 39391972 MACF1 Body
cg23485738 5.24 × 10−09 −0.023 −0.006 −0.032 0.068 6 32044171 SKIV2L Body
cg20069688 4.22 × 10−11 −0.026 −0.005 0.015 0.134 6 32049028 STK19 Body
cg24641186 5.72 × 10−23 0.036 0.027 0.011 0.188 6 50912106 TFAP2B Body
cg00207280 2.59 × 10−10 0.016 0.010 −0.001 0.231 8 126510575 TRIB1 TSS1500
cg07570723 1.53 × 10−12 0.024 0.013 0.002 0.338 1 39647825 KIAA0754 5′UTR
cg09247060 3.22 × 10−27 0.037 0.024 0.014 0.409 6 50895762 TFAP2B Body
cg27260772 1.03 × 10−16 0.032 0.031 0.020 0.422 6 50899161 TFAP2B Body
cg24161652 2.25 × 10−10 0.026 0.020 0.008 0.433 6 50921818 TFAP2B 3′UTR
cg02244386 4.45 × 10−08 −0.020 −0.007 −0.017 0.434 2 165182240 GRB14 Body
cg07737781 2.39 × 10−22 0.036 0.031 0.022 0.437 7 72676802 MLXIPL 1stExon
cg19620724 2.11 × 10−24 0.038 0.027 0.018 0.461 6 50918811 TFAP2B Body
cg10092878 6.05 × 10−25 0.038 0.031 0.039 0.472 7 72676795 MLXIPL First exon
cg24366557 2.51 × 10−32 0.040 0.034 0.028 0.569 6 50895609 TFAP2B Body
cg22282405 3.01 × 10−24 0.036 0.032 0.027 0.686 6 50918641 TFAP2B Body
cg07103129 7.92 × 10−28 0.040 0.031 0.026 0.703 6 50895923 TFAP2B Body
cg21317965 5.58 × 10−12 0.026 0.019 0.014 0.720 6 50911809 TFAP2B Body
cg23015341 4.29 × 10−24 0.035 0.023 0.021 0.843 6 50921300 TFAP2B 3′UTR
cg13824302 2.01 × 10−07 0.021 0.010 0.009 0.929 7 72677002 MLXIPL TSS200
cg08876103 3.17 × 10−19 −0.028 Convergence failure    1 39344910 MACF1 Body
  1. P diff is the significance value between the betas in the MetS and non-MetS groups. Italicized CpGs are nominally significant by P diff.