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Figure 7 | Clinical Epigenetics

Figure 7

From: Vitamin B12 insufficiency induces cholesterol biosynthesis by limiting s-adenosylmethionine and modulating the methylation of SREBF1 and LDLR genes

Figure 7

Effect of vitamin B 12 on human adipose tissue ex vivo . mRNA expression of genes regulating cholesterol biosynthesis in adipocytes; (A) SREBF1, (B) SREBF2, (C) LDLR, and (D) HMGCR. Each group was a minimum of n = 5. Values are mean ± SEM. *P ≤ 0.05; **P ≤ 0.01, ***P ≤ 0.001, P value compared to control.

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