Table 1 Analysis of the methylation at the imprinting center region 1 ( ICR1 ) and ICR2 on 11p15 in clonal fibroblasts
ICR1 methylation (mean; M1–M4) | ICR1 methylation (single methylation sites) | ICR2 methylation | |||||
|---|---|---|---|---|---|---|---|
M1 | M2 | M3 | M4 | ||||
SRShypo | S1sh_6 | 0 ± 0 | 0 ± 0 | 0 ± 0 | 1 ± 1 | 0 ± 0 | 50 ± 3 |
S1sh_8 | 0 ± 0 | 0 ± 0 | 0 ± 0 | 1 ± 0 | 0 ± 0 | 52 ± 6 | |
S5lo_10 | 0 ± 0 | 1 ± 0 | 0 ± 0 | 1 ± 1 | 0 ± 0 | 45 ± 3 | |
S2lo_7 | 1 ± 1 | 0 ± 0 | 0 ± 0 | 1 ± 1 | 2 ± 2 | 42 ± 7 | |
S2lo_1 | 1 ± 2 | 0 ± 0 | 0 ± 0 | 5 ± 2 | 0 ± 0 | 48 ± 2 | |
S1sh_12 | 1 ± 2 | 0 ± 0 | 0 ± 0 | 5 ± 2 | 0 ± 0 | 55 ± 5 | |
S5sh_11 | 2 ± 2 | 0 ± 0 | 0 ± 0 | 3 ± 1 | 5 ± 5 | 51 ± 4 | |
S3lo_9 | 8 ± 10 | 1 ± 1 | 0 ± 0 | 3 ± 1 | 28 ± 1 | 33 ± 3 | |
SRSnormo | S3sh_19 | 39 ± 10 | 26 ± 8 | 2 ± 1 | 53 ± 3 | 46 ± 0 | 49 ± 1 |
S5lo_9 | 33 ± 11 | 13 ± 2 | 32 ± 8 | 46 ± 7 | 41 ± 2 | 51 ± 3 | |
S2sh_1 | 30 ± 16 | 29 ± 3 | 29 ± 1 | 45 ± 5 | 47 ± 0 | 45 ± 7 | |
S1sh_9 | 43 ± 17 | 35 ± 6 | 19 ± 2 | 60 ± 12 | 60 ± 0 | 52 ± 5 | |
S1lo_7 | 55 ± 16 | 40 ± 3 | 37 ± 2 | 55 ± 7 | 86 ± 8 | 46 ± 2 | |
Cnormo | K3li_3 | 45 ± 11 | 27 ± 4 | 41 ± 4 | 50 ± 4 | 64 ± 1 | 53 ± 3 |
K2li_17 | 44 ± 9 | 38 ± 2 | 41 ± 6 | 53 ± 2 | 54 ± 1 | 60 ± 3 | |
K3re_12 | 39 ± 6 | 28 ± 4 | 46 ± 1 | 39 ± 1 | 44 ± 2 | 61 ± 5 | |
K1li_5 | 44 ± 4 | 28 ± 2 | 45 ± 6 | 49 ± 1 | 43 ± 9 | 59 ± 6 | |