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Table 1 Sample characteristics and number of samples whose CpG islands for each gene were successfully amplified for EpiTYPER analysis

From: Quantitative survey of multiple CpGs from 5 genes identifies CpG methylation panel discriminating between high- and low-grade cervical intraepithelial neoplasia

Stages ( N )

Mean Age ± SD

LMX1A

SOX1

ONECUT1

NKX6.1

PAX1

Normal (16)

48.3 ± 10.4

16

15

16

15

16

CIN I (31)

43.6 ± 11.2

23

24

31

30

22

CIN II + III(53)

41.0 ± 7.8

39

45

47

35

34

Total (100)

 

78

84

94

80

72

  1. PAX1: paired box 1; SOX1: SRY (sex determining region Y)-box 1; LMX1A: LIM homeobox transcription factor 1, alpha; NKX6-1: NK6 homeobox 1; ONECUT1: one cut homeobox 1; CIN: cervical intraepithelial neoplasia; SD: standard deviation.