Figure 3

The methylation patterns of the five genes. (A) Dot plot of the methylation levels for each gene. Each dot represents a sample, with methylation level averaged over all CpG units analyzed for the gene. (B) Bar graph of the methylation levels of individual CpG units. Open and filled columns denote CIN I/normal and CIN II/III group, respectively. Each bar represents mean methylation of all samples in the group. Error bars indicate SEM; *P < 0.05 for Mann-Whitney U test.